Evidence map›Paper›PMID 28729901›Full record

ArticleJournal of materials chemistry. B2017

Aptamer-functionalized neural recording electrodes for the direct measurement of cocaine in vivo.

I Mitch Taylor, Zhanhong Du, Emma T Bigelow, James R Eles, Anthony R Horner, Kasey A Catt, Stephen G Weber, Brian G Jamieson, X Tracy Cui

Abstract read
In one paragraph

Article in Journal of materials chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
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  6. Review
  7. In vivo microelectrode arrays for neuroscience.Nature reviews. Methods primers · 2025
    Article
  8. Article
  9. Article
  10. Applications of 2D Nanomaterials in Neural Interface.International journal of molecular sciences · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Real-Time,ACS sensors · 2022
    Review
  19. Article
  20. Semi-Implantable Bioelectronics.Nano-micro letters · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

I Mitch TaylorDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Zhanhong DuDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Emma T BigelowDiagnostic Biochips, Glen Burnie, MD 21061, USA.
James R ElesDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Anthony R HornerDepartment of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Kasey A CattDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Stephen G WeberDepartment of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Brian G JamiesonDiagnostic Biochips, Glen Burnie, MD 21061, USA.
X Tracy CuiDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA.
University of Pittsburgh · USParents' Place of Maryland · US

Funding

Fast Online Microdialysis/Liquid Chromatography for Monoamine NeurotransmittersR01MH104386 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WEBER, STEPHEN G. · 2014 to 2017
$1.3M
Neural probe for high spatial and temporal resolution detection of cocaine and GAR43DA035545 · NIDA · DIAGNOSTIC BIOCHIPS, INC. · PI JAMIESON, BRIAN GLENN · 2013 to 2014
$660k
Neural Probe for high spatial and temporal resolution detection of cocaine and suR43DA036264 · NIDA · DIAGNOSTIC BIOCHIPS, INC. · PI JAMIESON, BRIAN GLENN · 2013 to 2014
$637k
Microfabricated Neural Probe for the Rapid Detection of Multiple Neurochemicals IR43AA022030 · NIAAA · DIAGNOSTIC BIOCHIPS, INC. · PI JAMIESON, BRIAN GLENN · 2013 to 2014
$380k
NIAAA NIH HHS R43 AA022030NIDA NIH HHS R43 DA035545NIDA NIH HHS R43 DA036264NIMH NIH HHS R01 MH104386
6 · The paper itself

Abstract

Cocaine is a highly addictive psychostimulant that acts through competitive inhibition of the dopamine transporter. In order to fully understand the region specific neuropathology of cocaine abuse and addiction, it is unequivocally necessary to develop cocaine sensing technology capable of directly measuring real-time cocaine transient events local to different brain regions throughout the pharmacokinetic time course of exposure. We have developed an electrochemical aptamer-based

Indexed as

aptamercocainein vivoneural recording probesensorsquare wave voltammetry

Identifiers

PMID28729901
PMCPMC5512874
OpenAlexW2592252315

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.