Evidence map›Paper›PMID 28729680›Full record

ArticleScientific reports2017

The use of radiocobalt as a label improves imaging of EGFR using DOTA-conjugated Affibody molecule.

Javad Garousi, Ken G Andersson, Johan H Dam, Birgitte B Olsen, Bogdan Mitran, Anna Orlova, Jos Buijs, Stefan Ståhl, John Löfblom, Helge Thisgaard and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology.International journal of molecular sciences · 2021
    Review
  5. Article
  6. Review
  7. Scientific reports · 2021
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. PET radiometals for antibody labeling.Journal of labelled compounds & radiopharmaceuticals · 2018
    Review
  17. Article
  18. Cyclotron production and radiochemical separation ofApplied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Javad GarousiDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Ken G AnderssonDepartment of Protein Technology, KTH - Royal Institute of Technology, Stockholm, Sweden.
Johan H DamDepartment of Nuclear Medicine, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense, Denmark.ORCID 0000-0001-6577-7011
Birgitte B OlsenDepartment of Nuclear Medicine, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense, Denmark.
Bogdan MitranDivision of Molecular Imaging, Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
Anna OrlovaDivision of Molecular Imaging, Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
Jos BuijsDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-3955-1320
Stefan StåhlDepartment of Protein Technology, KTH - Royal Institute of Technology, Stockholm, Sweden.
John LöfblomDepartment of Protein Technology, KTH - Royal Institute of Technology, Stockholm, Sweden.
Helge ThisgaardDepartment of Nuclear Medicine, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense, Denmark.
Vladimir TolmachevDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. vladimir.tolmachev@igp.uu.se.
Uppsala University · SEKTH Royal Institute of Technology · SEOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several anti-cancer therapies target the epidermal growth factor receptor (EGFR). Radionuclide imaging of EGFR expression in tumours may aid in selection of optimal cancer therapy. The

Indexed as

Imaging, Three-DimensionalAnimalsCell Line, TumorCoordination ComplexesErbB ReceptorsFemaleHeterocyclic Compounds, 1-RingMice, Inbred BALB CMice, NudePositron-Emission TomographyRadioisotopesRecombinant Fusion ProteinsTissue DistributionTomography, X-Ray ComputedXenograft Model Antitumor AssaysCoordination ComplexesErbB ReceptorsHeterocyclic Compounds, 1-Ringindium-111-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acidRadioisotopesRecombinant Fusion Proteins

Identifiers

PMID28729680
PMCPMC5519605
OpenAlexW2735840021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.