Evidence map›Paper›PMID 28729485›Full record

ArticleScience (New York, N.Y.)2017

Response to Comments on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport".

Elizabeth O'Brien, Marilyn E Holt, Matthew K Thompson, Lauren E Salay, Aaron C Ehlinger, Walter J Chazin, Jacqueline K Barton

Open access · greenAbstract readComment
In one paragraph

Article in Science (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elizabeth O'BrienDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0003-2889-1688
Marilyn E HoltDepartments of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN 37235, USA.ORCID 0000-0002-3164-869X
Matthew K ThompsonDepartments of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN 37235, USA.ORCID 0000-0003-1373-0072
Lauren E SalayDepartments of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN 37235, USA.ORCID 0000-0001-8513-1891
Aaron C EhlingerDepartments of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN 37235, USA.ORCID 0000-0003-2036-7355
Walter J ChazinDepartments of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN 37235, USA. jkbarton@caltech.edu walter.j.chazin@vanderbilt.edu.ORCID 0000-0002-2180-0790
Jacqueline K BartonDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA. jkbarton@caltech.edu walter.j.chazin@vanderbilt.edu.ORCID 0000-0001-9883-1600
Vanderbilt University · USCalifornia Institute of Technology · US

Funding

BIOCHEMICAL &CHEMICAL TRAINING FOR CANCER RESEARCHT32CA009582 · NCI · VANDERBILT UNIVERSITY · PI David K Cortez · 1987 to 2026
$8.8M
MOLECULAR BIOPHYSICS TRAINING PROGRAM AT VANDERBILTT32GM008320 · NIGMS · VANDERBILT UNIVERSITY · PI CHAZIN, WALTER J. · 1989 to 2023
$7.9M
Structural Biology of Multi-Domain Proteins and Multi-Protein Machinery in DNA Replication and RepairR35GM118089 · NIGMS · VANDERBILT UNIVERSITY · PI WALTER J. CHAZIN · 2016 to 2026
$4.9M
Structural Basis for RPA Functions in DNA ProcessingR01GM065484 · NIGMS · VANDERBILT UNIVERSITY · PI CHAZIN, WALTER J. · 2003 to 2015
$3.9M
NCI NIH HHS T32 CA009582NIGMS NIH HHS R01 GM065484NIGMS NIH HHS R35 GM118089NIGMS NIH HHS T32 GM008320
6 · The paper itself

Abstract

Baranovskiy

Indexed as

Oxidation-ReductionBiological TransportDNADNA PrimaseElectron TransportHumansDNADNA Primase

Identifiers

PMID28729485
PMCPMC5935490
OpenAlexW2739001523

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.