Evidence map›Paper›PMID 28729440›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk.

Rowena Smith, Yu-Ting Huang, Tian Tian, Dominika Vojtasova, Oscar Mesalles-Naranjo, Steven M Pollard, Thomas Pratt, David J Price, Vassiliki Fotaki

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  9. Article
  10. MicroRNA Signatures of the Developing Primate Fovea.Frontiers in cell and developmental biology · 2021
    Article
  11. Article
  12. Article
  13. Knockdown ofAging · 2020
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rowena SmithEdinburgh Medical School, Biomedical Sciences, Centre for Integrative Physiology, Edinburgh, EH8 9XD, United Kingdom.
Yu-Ting HuangEdinburgh Medical School, Biomedical Sciences, Centre for Integrative Physiology, Edinburgh, EH8 9XD, United Kingdom.
Tian TianEdinburgh Medical School, Biomedical Sciences, Centre for Integrative Physiology, Edinburgh, EH8 9XD, United Kingdom.
Dominika VojtasovaEdinburgh Medical School, Biomedical Sciences, Centre for Integrative Physiology, Edinburgh, EH8 9XD, United Kingdom.
Oscar Mesalles-NaranjoInformation Service Division, NHS National Services Scotland, Edinburgh, EH12 9EB, United Kingdom.
Steven M PollardMedical Research Council Centre for Regenerative Medicine, Edinburgh, EH16 4UU, United Kingdom, and.ORCID 0000-0001-6428-0492
Thomas PrattEdinburgh Medical School, Biomedical Sciences, Centre for Integrative Physiology, Edinburgh, EH8 9XD, United Kingdom.ORCID 0000-0002-7105-3527
David J PriceEdinburgh Medical School, Biomedical Sciences, Centre for Integrative Physiology, Edinburgh, EH8 9XD, United Kingdom.
Vassiliki FotakiEdinburgh Medical School, Biomedical Sciences, Centre for Integrative Physiology, Edinburgh, EH8 9XD, United Kingdom, vfotaki@ed.ac.uk.ORCID 0000-0001-9112-3257
University of Edinburgh · GBEdinburgh Cancer Research · GBNational Health Service Scotland · GB

Funding

Cancer Research UK 17368Medical Research Council MR/J013137/1Wellcome Trust
6 · The paper itself

Abstract

During vertebrate eye morphogenesis, a transient fissure forms at its inferior part, known as the optic fissure. This will gradually close, giving rise to a healthy, spherical optic cup. Failure of the optic fissure to close gives rise to an ocular disorder known as coloboma. During this developmental process,

Indexed as

AnimalsFemaleForkhead Transcription FactorsMaleMiceMice, Inbred C57BLMice, Inbred CBAMice, KnockoutNerve Tissue ProteinsOptic DiskPregnancyTranscription FactorsWnt ProteinsForkhead Transcription FactorsFoxg1 protein, mouseNerve Tissue ProteinsTranscription FactorsWnt8b protein, mouseWnt ProteinsColobomaFoxg1mouseoptic cupoptic fissureWnt8b

Identifiers

PMID28729440
PMCPMC5559767
OpenAlexW2737795413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.