Evidence map›Paper›PMID 28729434›Full record

ArticleThe EMBO journal2017

Cohesins and condensins orchestrate the 4D dynamics of yeast chromosomes during the cell cycle.

Luciana Lazar-Stefanita, Vittore F Scolari, Guillaume Mercy, Héloise Muller, Thomas M Guérin, Agnès Thierry, Julien Mozziconacci, Romain Koszul

Abstract read
In one paragraph

Article in The EMBO journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed.

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  6. A Translocation within thebioRxiv : the preprint server for biology · 2026
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  9. A data-driven chromatin model reveals spatial and dynamic features of genome organization.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Article
  11. Organization principles of dynamic three-dimensional genome architecture associated with centromere clustering states.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  15. Article
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Luciana Lazar-StefanitaInstitut Pasteur, Department Genomes and Genetics, Unité Régulation Spatiale des Génomes, Paris, France.
Vittore F ScolariInstitut Pasteur, Department Genomes and Genetics, Unité Régulation Spatiale des Génomes, Paris, France.
Guillaume MercyInstitut Pasteur, Department Genomes and Genetics, Unité Régulation Spatiale des Génomes, Paris, France.
Héloise MullerInstitut Pasteur, Department Genomes and Genetics, Unité Régulation Spatiale des Génomes, Paris, France.
Thomas M GuérinLaboratoire Télomères et Réparation du Chromosome, CEA, INSERM, UMR 967, IRCM, Université Paris-Saclay, Fontenay-aux-Roses, France.
Agnès ThierryInstitut Pasteur, Department Genomes and Genetics, Unité Régulation Spatiale des Génomes, Paris, France.
Julien MozziconacciSorbonne Universités, Theoretical Physics for Condensed Matter Lab, UPMC Université Paris 06, Paris, France mozziconacci@lptmc.jussieu.fr romain.koszul@pasteur.fr.ORCID 0000-0001-5652-0302
Romain KoszulInstitut Pasteur, Department Genomes and Genetics, Unité Régulation Spatiale des Génomes, Paris, France mozziconacci@lptmc.jussieu.fr romain.koszul@pasteur.fr.ORCID 0000-0002-3086-1173

Funding

European Research Council 260822
6 · The paper itself

Abstract

Duplication and segregation of chromosomes involves dynamic reorganization of their internal structure by conserved architectural proteins, including the structural maintenance of chromosomes (SMC) complexes cohesin and condensin. Despite active investigation of the roles of these factors, a genome-wide view of dynamic chromosome architecture at both small and large scale during cell division is still missing. Here, we report the first comprehensive 4D analysis of the higher-order organization of the

Indexed as

Cell CycleAdenosine TriphosphatasesCell Cycle ProteinsChromosomal Proteins, Non-HistoneChromosomes, FungalCohesinsDNA-Binding ProteinsMultiprotein ComplexesSaccharomyces cerevisiaeSpatio-Temporal AnalysisAdenosine TriphosphatasesCell Cycle ProteinsChromosomal Proteins, Non-HistoneCohesinscondensin complexesDNA-Binding ProteinsMultiprotein Complexeschromosome segregationHi‐Cloop extrusionreplication profileSMC

Identifiers

PMID28729434
PMCPMC5599795

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.