Evidence map›Paper›PMID 28729421›Full record

ArticleThe Journal of biological chemistry2017

The small G protein RAS2 is involved in the metabolic compensation of the circadian clock in the circadian model

Norbert Gyöngyösi, Anita Szőke, Krisztina Ella, Krisztina Káldi

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. A Compensated Clock: Temperature and Nutritional Compensation Mechanisms Across Circadian Systems.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  5. Circadian regulation of metabolism across photosynthetic organisms.The Plant journal : for cell and molecular biology · 2023
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Norbert GyöngyösiFrom the Department of Physiology, Semmelweis University, Tűzoltó u. 37-47, 1094 Budapest, Hungary.
Anita SzőkeFrom the Department of Physiology, Semmelweis University, Tűzoltó u. 37-47, 1094 Budapest, Hungary.
Krisztina EllaFrom the Department of Physiology, Semmelweis University, Tűzoltó u. 37-47, 1094 Budapest, Hungary.
Krisztina KáldiFrom the Department of Physiology, Semmelweis University, Tűzoltó u. 37-47, 1094 Budapest, Hungary kaldi.krisztina@med.semmelweis-univ.hu.ORCID 0000-0002-5724-0182
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence from both experimental and clinical investigations indicates a tight interaction between metabolism and circadian timekeeping; however, knowledge of the underlying mechanism is still incomplete. Metabolic compensation allows circadian oscillators to run with a constant speed at different substrate levels and, therefore, is a substantial criterion of a robust rhythm in a changing environment. Because previous data have suggested a central role of RAS2-mediated signaling in the adaptation of yeast to different nutritional environments, we examined the involvement of RAS2 in the metabolic regulation of the clock in the circadian model organism

Indexed as

Circadian ClocksModels, BiologicalNeurospora crassaras Proteinsras ProteinscAMPcircadian rhythmentrainmentglucose compensationNeurosporaRas proteinsmall GTPase

Identifiers

PMID28729421
PMCPMC5592671
OpenAlexW2738080218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.