Evidence map›Paper›PMID 28729384›Full record

ArticleClinical journal of the American Society of Nephrology : CJASN2017

Characteristics and Outcomes of Patients Discharged Home from an Emergency Department with AKI.

Rey R Acedillo, Ron Wald, Eric McArthur, Danielle Marie Nash, Samuel A Silver, Matthew T James, Michael J Schull, Edward D Siew, Michael E Matheny, Andrew A House and 1 more

Abstract read
In one paragraph

Article in Clinical journal of the American Society of Nephrology : CJASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Plasma Biomarkers of Kidney Tubule Health during Ambulatory AKI and Kidney Function Recovery in SPRINT.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Trial
  2. Article
  3. Article
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  5. Poisoning-Induced Acute Kidney Injury: A Review.Medicina (Kaunas, Lithuania) · 2024
    Review
  6. Aurantio-obtusin exerts an anti-inflammatory effect on acute kidney injury by inhibiting NF-κB pathway.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
  7. Article
  8. Epidemiology of Community-Acquired Acute Kidney Injury Among US Veterans.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Ethanol Extract ofNutrients · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Rey R AcedilloDivision of Nephrology, Department of Medicine, London Health Sciences Centre, London, Ontario, Canada.
Ron WaldDivision of Nephrology, Department of Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.
Eric McArthurInstitute for Clinical Evaluative Sciences, Ontario, Canada.
Danielle Marie NashInstitute for Clinical Evaluative Sciences, Ontario, Canada.
Samuel A SilverDivision of Nephrology, Department of Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.
Matthew T JamesDivision of Nephrology, Department of Medicine, Foothills Hospital, Calgary, Alberta, Canada.
Michael J SchullInstitute for Clinical Evaluative Sciences, Ontario, Canada.
Edward D SiewDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt Center for Kidney Disease and Integrated Program for AKI Research.
Michael E MathenyDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt Center for Kidney Disease and Integrated Program for AKI Research.
Andrew A HouseDivision of Nephrology, Department of Medicine, London Health Sciences Centre, London, Ontario, Canada.
Amit X GargDivision of Nephrology, Department of Medicine, London Health Sciences Centre, London, Ontario, Canada.

Funding

TRAINING PROGRAM IN ACADEMIC NEPHROLOGYT32DK007357 · NIDDK · STANFORD UNIVERSITY · PI CHERTOW, GLENN MATTHEW · 1986 to 2022
$4.8M
HSRD VA IIR 13-073NIDDK NIH HHS T32 DK007357
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPatients discharged home from an emergency department with AKI are not well described. This study describes their characteristics and outcomes and compares these outcomes to two referent groups. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a population-based retrospective cohort study in Ontario, Canada from 2003 to 2012 of 6346 patients aged ≥40 years who were discharged from the emergency department with AKI (defined using serum creatinine values). We analyzed the risk of all-cause mortality, receipt of acute dialysis, and hospitalization within 30 days after discharge. We used propensity score methods to compare all-cause mortality to two referent groups. We matched 4379 discharged patients to 4379 patients who were hospitalized from the emergency department with similar AKI stage. We also matched 6188 discharged patients to 6188 patients who were discharged home from the emergency department with no AKI.

resultsThere were 6346 emergency department discharges with AKI. The mean age was 69 years and 6012 (95%) had stage 1, 290 (5%) had stage 2, and 44 (0.7%) had stage 3 AKI. Within 30 days, 149 (2%) (AKI stage 1: 127 [2%]; stage 2: 15 [5%]; stage 3: seven [16%]) died, 22 (0.3%) received acute dialysis, and 1032 (16%) were hospitalized. An emergency department discharge versus hospitalization with AKI was associated with lower mortality (3% versus 12%; relative risk, 0.3; 95% confidence interval, 0.2 to 0.3). An emergency department discharge with AKI versus no AKI was associated with higher mortality (2% versus 1%; relative risk, 1.6; 95% confidence interval, 1.2 to 2.0).

conclusionsPatients discharged home from the emergency department with AKI are at risk of poor 30-day outcomes. A better understanding of care in this at-risk population is warranted, as are testing strategies to improve care.

Indexed as

Acute Kidney InjuryAgedCanadaConfidence IntervalscreatinineEmergency Service, HospitalhospitalizationHumansKidney Function TestsOntarioPatient DischargePropensity Scorerenal dialysisRetrospective StudiesRisk

Identifiers

PMID28729384
PMCPMC5544515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.