Evidence map›Paper›PMID 28729040›Full record

Observational studyAtencion primaria

[Long-term effects of intensive intervention on changes in lifestyle in patients with hyperfibrinogenaemia and moderate-high cardiovascular risk].

Laura Illamola Martin, Juan José Rodríguez Cristobal, Carlos Alonso-Villaverde, Betlem Salvador-González, Irene Moral Pelaez

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Atencion primaria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Laura Illamola MartinCAP Roger de Flor, EAP Dreta de l'Eixample, Barcelona, España. Electronic address: lauraillamola@hotmail.com.
Juan José Rodríguez CristobalCAP Florida Sud, Institut Català de la Salut (ICS), L'Hospitalet de Llobregat, Barcelona, España.
Carlos Alonso-VillaverdeCentre d'Investigació Cardiovascular CSIC-ICCC, Hospital Sant Pau, Barcelona, España.
Betlem Salvador-GonzálezCAP Florida Sud, Institut Català de la Salut (ICS), L'Hospitalet de Llobregat, Barcelona, España.
Irene Moral PelaezEAP Sardenya, Barcelona, España.
Institut Català de la Salut · ESConsorci d’Atenció Primària de Salut Barcelona Esquerra · ESEADA Business School · ESHospital de Sant Pau · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine whether the benefit on cardiovascular risk factors (CVRF) persists 5 years after an intensive intervention in lifestyle (LS) that lasted 2 years, in patients with hyperfibrinogenaemia and moderate or high cardiovascular risk.

designmulticentre prospective observational study. LOCATION: 13 Primary Care Centres in Barcelona and Baix Llobregat.

participantsA total of 300 patients who completed the EFAP study (146 intervention group, 154 control group).

interventionsThe EFAP study, conducted on patients with normal cholesterol and elevated fibrinogen showed that lifestyle interventions are effective in reducing CVRF. After the EFAP study, the 2 groups followed the usual controls, and re-assessed after 5 years. MAIN MEASUREMENTS: Age, gender, cardiovascular diseases (CVD) (diabetes, dyslipidaemia, hypertension, obesity), laboratory parameters (fibrinogen, glucose, full blood count, cholesterol, triglycerides), blood pressure, weight, height, body mass index (BMI), tobacco and alcohol use, REGICOR.

resultsAt 5 years, the intervention group had a lower abdominal circumference (98 and 101cm, respectively, P=.043), a lower weight (76.30 and 75.04kg, respectively, P<.001), and BMI (29.5 and 30.97kg/m

conclusionThe benefit of an intensive intervention in LS for 2 years to reduce CVRF persists at 5 years, but decreases its intensity over time. It is recommended to repeat the interventions periodically to maintain the beneficial effect on LS.

Indexed as

Cardiovascular DiseasesFibrinogenLife StyleAge FactorsBiomarkersBody Mass IndexBody WeightCase-Control StudiesDyslipidemiasFemaleFollow-Up StudiesHumansHypertensionMaleMiddle AgedObesityBiomarkersFibrinogenAbdominal circumferenceBody mass indexCardiovascular riskFibrinogenFibrinógenoÍndice de masa corporalIntervención en estilos de vidaInterventions on lifestyleObesidadObesityPerímetro abdominalRiesgo cardiovascular

Identifiers

PMID28729040
PMCPMC6836964
OpenAlexW2736815153

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.