Evidence map›Paper›PMID 28729016›Full record

ArticleMagnetic resonance imaging2017

Learning-based structurally-guided construction of resting-state functional correlation tensors.

Lichi Zhang, Han Zhang, Xiaobo Chen, Qian Wang, Pew-Thian Yap, Dinggang Shen

Abstract read
In one paragraph

Article in Magnetic resonance imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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  11. Exploring diagnosis and imaging biomarkers of Parkinson's disease via iterative canonical correlation analysis based feature selection.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Lichi ZhangDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, United States. Electronic address: lichi@med.unc.edu.
Han ZhangDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, United States.
Xiaobo ChenDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, United States.
Qian WangMed-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, China. Electronic address: wang.qian@sjtu.edu.cn.
Pew-Thian YapDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, United States. Electronic address: pewthian_yap@med.unc.edu.
Dinggang ShenDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, United States; Department of Brain and Cognitive Engineering, Korea University, Seoul 02841, Republic of Korea. Electronic address: dgshen@med.unc.edu.
University of North Carolina at Chapel Hill · USShanghai Jiao Tong University · CN

Funding

Assessing Large-scale Brain Connectivities in Mild Cognitive ImpairmentR01AG042599 · NIA · UNIVERSITY OF GEORGIA · PI LIU, TIANMING · 2013 to 2017
$1.4M
Diagnosis of Alzheimer's Disease Using Dynamic High-Order Brain NetworksR01EB022880 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2018
$1.1M
Robust White Matter Morphometry with Small DatabasesR01NS093842 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2018
$1.1M
NIA NIH HHS R01 AG042599NIBIB NIH HHS R01 EB022880NINDS NIH HHS R01 NS093842
6 · The paper itself

Abstract

Functional magnetic resonance imaging (fMRI) measures changes in blood-oxygenation-level-dependent (BOLD) signals to detect brain activities. It has been recently reported that the spatial correlation patterns of resting-state BOLD signals in the white matter (WM) also give WM information often measured by diffusion tensor imaging (DTI). These correlation patterns can be captured using functional correlation tensor (FCT), which is analogous to the diffusion tensor (DT) obtained from DTI. In this paper, we propose a noise-robust FCT method aiming at further improving its quality, and making it eligible for further neuroscience study. The novel FCT estimation method consists of three major steps: First, we estimate the initial FCT using a patch-based approach for BOLD signal correlation to improve the noise robustness. Second, by utilizing the relationship between functional and diffusion data, we employ a regression forest model to learn the mapping between the initial FCTs and the corresponding DTs using the training data. The learned forest can then be applied to predict the DTI-like tensors given the initial FCTs from the testing fMRI data. Third, we re-estimate the enhanced FCT by utilizing the DTI-like tensors as a feedback guidance to further improve FCT computation. We have demonstrated the utility of our enhanced FCTs in Alzheimer's disease (AD) diagnosis by identifying mild cognitive impairment (MCI) patients from normal subjects.

Indexed as

Diffusion Tensor ImagingMagnetic Resonance ImagingAdultAgedAlgorithmsAlzheimer DiseaseBrainCognitive DysfunctionCohort StudiesFemaleHealthy VolunteersHumansMachine LearningMaleModels, StatisticalNeurosciencesDTIFunctional correlation tensorRandom forestrs-fMRI

Identifiers

PMID28729016
PMCPMC5632586
OpenAlexW2735232030

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.