ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2017
Diagnostic delays in 537 symptomatic cases of Middle East respiratory syndrome coronavirus infection in Saudi Arabia.
Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Comparison of confirmed COVID-19 with SARS and MERS cases - Clinical characteristics, laboratory findings, radiographic signs and outcomes: A systematic review and meta-analysis.Reviews in medical virology · 2020Pooled it
- MERS transmission and risk factors: a systematic review.BMC public health · 2018Pooled it
- The time between symptom onset and various clinical outcomes: a statistical analysis of MERS-CoV patients in Saudi Arabia.Royal Society open science · 2024Article
- Article
- Estimating the Epidemic Size of Superspreading Coronavirus Outbreaks in Real Time: Quantitative Study.JMIR public health and surveillance · 2024Article
- Product of natural evolution (SARS, MERS, and SARS-CoV-2); deadly diseases, from SARS to SARS-CoV-2.Human vaccines & immunotherapeutics · 2021Article
- Climate factors and incidence of Middle East respiratory syndrome coronavirus.Journal of infection and public health · 2020Article
- Demographic Variations of MERS-CoV Infection among Suspected and Confirmed Cases: An Epidemiological Analysis of Laboratory-Based Data from Riyadh Regional Laboratory.BioMed research international · 2020Article
- A Review of Zoonotic Pathogens of Dromedary Camels.EcoHealth · 2019Review
- Development of a risk-prediction model for Middle East respiratory syndrome coronavirus infection in dialysis patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2018Article
- Factors associated with recovery delay in a sample of patients diagnosed by MERS-CoV rRT-PCR: A Saudi Arabian multicenter retrospective study.Influenza and other respiratory viruses · 2018Article
- Early identification of pneumonia patients at increased risk of Middle East respiratory syndrome coronavirus infection in Saudi Arabia.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2018Article
- Estimating survival rates in MERS-CoV patients 14 and 45 days after experiencing symptoms and determining the differences in survival rates by demographic data, disease characteristics and regions: a worldwide study.Epidemiology and infection · 2018Article
- The predictors of 3- and 30-day mortality in 660 MERS-CoV patients.BMC infectious diseases · 2017Article
- Main factors influencing recovery in MERS Co-V patients using machine learning.Journal of infection and public healthArticle
- Diagnostic delays in Middle East respiratory syndrome coronavirus patients and health systems.Journal of infection and public healthArticle
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Authors and funding
1 author at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough the literature indicates that patient delays in seeking medical support for Middle East respiratory syndrome coronavirus (MERS-CoV) infections are associated with poor clinical outcomes, delays in the diagnosis itself remain poorly understood in these patients. This study aimed to determine the median time interval from symptom onset to a confirmed diagnosis and to identify the potential predictors of this interval in Saudi Arabian MERS patients.
methodsThis was a retrospective study of patients with confirmed MERS who were publicly reported by the World Health Organization (WHO).
resultsFive hundred and thirty-seven symptomatic cases of MERS-CoV infection were included. The median time interval between symptom onset and confirmation of the MERS diagnosis was 4 days (interquartile range 2-7 days), ranging from 0 to 36 days. According to the negative binomial model, the unadjusted rate ratio (RR) of delays in the diagnosis was significantly higher in older patients (>65 years) (RR 1.42), non-healthcare workers (RR 1.74), patients with severe illness (RR 1.22), those with an unknown source of infection (RR 1.84), and those who had been in close contact with camels (RR 1.74). After accounting for confounders, the adjusted rate ratio (aRR) of delays in the diagnosis was independently associated with unknown source of infection (aRR 1.68) and close contact with camels (aRR 1.58).
conclusionsThe time interval from symptom onset to diagnosis was greater in older patients, non-healthcare workers, patients with severe illness, patients with an unknown source of infection, and patients who had been in close contact with camels. The findings warrant educational interventions to raise general public awareness of the importance of early symptom notification.
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