Evidence map›Paper›PMID 28728600›Full record

ArticleBMC research notes2017

Comparison of the polyphenolic profile and antibacterial activity of the leaves, fruits and flowers of Rhododendron ambiguum and Rhododendron cinnabarinum.

Abhinandan Shrestha, Ahmed Rezk, Inamullah Hakeem Said, Victoria von Glasenapp, Rachelle Smith, Matthias S Ullrich, Hartwig Schepker, Nikolai Kuhnert

Abstract read
In one paragraph

Article in BMC research notes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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  3. UPLC-ESI/MSFrontiers in chemistry · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abhinandan ShresthaDepartment of Life Science & Chemistry, Jacobs University Bremen, Campus Ring 1, 28759, Bremen, Germany.
Ahmed RezkDepartment of Life Science & Chemistry, Jacobs University Bremen, Campus Ring 1, 28759, Bremen, Germany.
Inamullah Hakeem SaidDepartment of Life Science & Chemistry, Jacobs University Bremen, Campus Ring 1, 28759, Bremen, Germany.
Victoria von GlasenappDepartment of Life Science & Chemistry, Jacobs University Bremen, Campus Ring 1, 28759, Bremen, Germany.
Rachelle SmithDepartment of Life Science & Chemistry, Jacobs University Bremen, Campus Ring 1, 28759, Bremen, Germany.
Matthias S UllrichDepartment of Life Science & Chemistry, Jacobs University Bremen, Campus Ring 1, 28759, Bremen, Germany.
Hartwig SchepkerStiftung Bremer Rhododendronpark, Deliusweg 40, 28359, Bremen, Germany.
Nikolai KuhnertDepartment of Life Science & Chemistry, Jacobs University Bremen, Campus Ring 1, 28759, Bremen, Germany. n.kuhnert@jacobs-university.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRhododendron species have been traditionally used in countries like China, Nepal, Russia and North America for treating human diseases. These species are known to be a good source of polyphenolic plant secondary plant metabolites. They are known to have beneficial health properties for humans and have been used to treat diseases like asthma, skin diseases. In this contribution we investigate the phenolic profile and antibacterial activity of extracts from several plant organs including for the first time from leaves of different development stages.

methodsIn this study, the polyphenolic profile of fruits, flowers and leaves of different ages of Rhododendron ambiguum and Rhododendron cinnabarinum were studied by using HPLC-MS and compounds identified based on high resolution masses and identity of tandem mass spectra, UV/VIS spectra and retention times if compared to standards.

resultsFifty-nine different polyphenols including isomers were identified in these species by their fragmentation pattern and high resolution data. Also, the antibacterial activity of these parts (leaves, fruits and flowers) against gram-positive bacteria was studied.

conclusionThe leaves and fruits contained more polyphenols than the flowers. With the exception of flowers, the fruits and leaves of both species were also determined to have a significant antibacterial effect against four gram-positive bacteria.

Indexed as

Anti-Bacterial AgentsFlowersFruitPlant LeavesPolyphenolsRhododendronChromatography, High Pressure LiquidTandem Mass SpectrometryAnti-Bacterial AgentsPolyphenolsAntibacterialFlowersFruitsLeavesPolyphenolsRhododendron

Identifiers

PMID28728600
PMCPMC5520227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.