SynthesisLeukemia & lymphoma2018
Pregnancy and child health outcomes in pediatric and young adult leukemia and lymphoma survivors: a systematic review.
Synthesis in Leukemia & lymphoma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Non-genetic risk factors of miscarriage: a comprehensive umbrella review of systematic review and meta-analysis.Reproductive health · 2025Pooled it
- Maternal and perinatal outcomes following a diagnosis of Hodgkin lymphoma during or prior to pregnancy: A systematic review.BJOG : an international journal of obstetrics and gynaecology · 2023Pooled it
- Leukemia during pregnancy and survivorship: gestational age-stratified multidisciplinary management framework.Clinical and experimental medicine · 2026Review
- Utilisation of healthcare in children born to lymphoma survivors in Sweden.Acta oncologica (Stockholm, Sweden) · 2025Article
- An Account of Acute Myeloid Leukemia Complicating Pregnancy and Literature Review.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Association of platinum-based chemotherapy with live birth and infertility in female survivors of adolescent and young adult cancer.Fertility and sterility · 2024Article
- Risk of adverse birth outcomes after adolescent and young adult cancer.JNCI cancer spectrum · 2024Article
- Making sense of the risks: what to tell adolescents and young adults diagnosed with cancer during pregnancy.Journal of the National Cancer Institute · 2023Article
- Effect of chemotherapy on the uterus of young adult cancer survivors.F&S reports · 2022Article
- Web-Based Research Trends on Child and Adolescent Cancer Survivors Over the Last 5 Years: Text Network Analysis and Topic Modeling Study.Journal of medical Internet research · 2022Article
- [Diagnosis and treatment of acute leukemia during pregnancy].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2022Article
- Congenital Malformations and Perinatal Deaths Among the Children of Atomic Bomb Survivors: A Reappraisal.American journal of epidemiology · 2021Article
- Health outcomes in offspring born to survivors of childhood cancers following assisted reproductive technologies.Journal of cancer survivorship : research and practice · 2021Article
- [Management of patients with lymphoma in pregnancy].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2020Article
- Lymphoma Occurring During Pregnancy: Current Diagnostic and Therapeutic Approaches.Current oncology reports · 2020Review
- Ovarian stimulation is a safe and effective fertility preservation option in the adolescent and young adult population.Journal of assisted reproduction and genetics · 2020Article
- Ambulant health care utilisation among children of childhood cancer survivors in Germany.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Risk of Being Born Preterm in Offspring of Cancer Survivors: A National Cohort Study.Frontiers in oncology · 2020Article
- Perceived infertility and contraceptive use in the female, reproductive-age cancer survivor.Fertility and sterility · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
As long-term survival is high for children and young adults diagnosed with leukemia and lymphoma, delineating maternal, fetal and offspring health risks is important to their family planning. This systematic review examined data comparing these health risks between leukemia and lymphoma survivors and women without a history of cancer. Following a search of Embase, PubMed, CINAHL, Cochrane, and Web of Science, 142 articles were screened and 18 were included in this review. No higher risks of spontaneous abortion, maternal diabetes and anemia, stillbirth, birth defects, or childhood cancer in offspring were observed in survivors compared to controls. Important to counseling and clinical care, live birth rates were lower, while preterm birth and low birth weight risks were modestly higher in survivors compared to controls. Findings were largely reassuring but highlight the lack of data on maternal cardiopulmonary risks, differential risk by cancer treatment type, and interventions to decrease these risks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.