Evidence map›Paper›PMID 28728026›Full record

ArticleNeuron2017

Parallel Interdigitated Distributed Networks within the Individual Estimated by Intrinsic Functional Connectivity.

Rodrigo M Braga, Randy L Buckner

2 registry-linked trialsAbstract read
In one paragraph

Article in Neuron, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 405 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
405citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04748146 nawithdrawnnot on this mapstarted 2026, after this paper: background citation

Causal mechanisms of distributed brain network function during episodic memory retrieval

TypeinterventionalSponsorNorthwestern UniversityRan2026 to 2027Enrolled0ConditionsEpisodic MemoryArmsBrain stimulation
NCT07024875 recruitingnot on this mapstarted 2025, after this paper: background citation

Precision Neuroimaging of Parkinson's Disease

Typeobservational_patient_registrySponsorWashington University School of MedicineRan2025 to 2031Enrolled120ConditionsParkinsons Disease (PD)
3 · Its place in the literature

Who cites it

405 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  5. Common and distinct correlates of construction and elaboration of episodic-autobiographical memory: An ALE meta-analysis.Cortex; a journal devoted to the study of the nervous system and behavior · 2023
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  10. Individualized Network Topography in Pre-adolescent Children and Adults Using Naturalistic Precision fMRI.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
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  14. Increased Attentive Use Is Linked to More Idiosyncratic Functional Connections.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
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345 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rodrigo M BragaDepartment of Psychology, Center for Brain Science, Harvard University, Cambridge, MA 02138, USA; The Computational, Cognitive & Clinical Neuroimaging Laboratory, Hammersmith Hospital Campus, Imperial College London, London W12 0NN, UK; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA. Electronic address: rodrigo.braga@imperial.ac.uk.
Randy L BucknerDepartment of Psychology, Center for Brain Science, Harvard University, Cambridge, MA 02138, USA; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA; Department of Psychiatry, Massachusetts General Hospital, Charlestown, MA 02129, USA. Electronic address: randy_buckner@harvard.edu.

Funding

The neural network of OCD, linking NHP and human studiesP50MH106435 · NIMH · UNIVERSITY OF ROCHESTER · PI Suzanne N Haber · 2015 to 2026
$28.9M
Upgrade Siemens MAGNETOM Trio to MAGNETOM Prisma Fit 3T Human MRI SystemS10OD020039 · OD · HARVARD UNIVERSITY · PI BUCKNER, RANDY L · 2015 to 2015
$600k
NIH HHS S10 OD020039NIMH NIH HHS P50 MH106435Wellcome Trust
6 · The paper itself

Abstract

Certain organizational features of brain networks present in the individual are lost when central tendencies are examined in the group. Here we investigated the detailed network organization of four individuals each scanned 24 times using MRI. We discovered that the distributed network known as the default network is comprised of two separate networks possessing adjacent regions in eight or more cortical zones. A distinction between the networks is that one is coupled to the hippocampal formation while the other is not. Further exploration revealed that these two networks were juxtaposed with additional networks that themselves fractionate group-defined networks. The collective networks display a repeating spatial progression in multiple cortical zones, suggesting that they are embedded within a broad macroscale gradient. Regions contributing to the newly defined networks are spatially variable across individuals and adjacent to distinct networks, raising issues for network estimation in group-averaged data and applied endeavors, including targeted neuromodulation.

Indexed as

Brain MappingCerebral CortexHippocampusHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingNerve NetNeural Pathwaysassociation cortexbrain systemsdefault networkdorsal attention networkfrontoparietal networkhippocampusmemory

Identifiers

PMID28728026
PMCPMC5519493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.