SynthesisEnvironmental research2017
Environmental exposures and pediatric kidney function and disease: A systematic review.
Synthesis in Environmental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Bisphenol a Exposure and Kidney Diseases: Systematic Review, Meta-Analysis, and NHANES 03-16 Study.Biomolecules · 2021Pooled it
- Environmental exposures and pediatric kidney health.Pediatric research · 2026Review
- Berberine nanoemulsion against nephrotoxicity induced by bisphenol a in rats during pre-puberty stage.Toxicology reports · 2026Article
- Estimating the environmental burden of disease in children and adolescents in Germany: limitations and possible solutions.Frontiers in public health · 2026Article
- Analytical Determination of Heavy Metals in Water Using Carbon-Based Materials.Molecules (Basel, Switzerland) · 2025Review
- Insulin like growth factor binding protein 7 activate JNK/ERK signaling to aggravate uranium-induced renal cell cytotoxicity.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Endocrine Disruptors in Child Obesity and Related Disorders: Early Critical Windows of Exposure.Current nutrition reports · 2025Review
- The global health burden of pediatric chronic kidney disease: An analysis of the Global Burden of Disease database from 1990 to 2021.PloS one · 2025Article
- Hospitalization risks associated with floods in a multi-country study.Nature water · 2025Article
- Protective Effect of Resveratrol on Kidney Disease and Hypertension Against Microplastics Exposure in Male Juvenile Rats.Antioxidants (Basel, Switzerland) · 2024Article
- Protecting our future: environmental hazards and children's health in the face of environmental threats: a comprehensive overview.Clinical and experimental pediatrics · 2024Article
- Adverse effects of triclosan exposure on health and potential molecular mechanisms.The Science of the total environment · 2023Review
- Article
- Prenatal and early childhood critical windows for the association of nephrotoxic metal and metalloid mixtures with kidney function.Environment international · 2022Article
- Review
- Critical windows of perinatal particulate matter (PMEnvironmental research · 2022Article
- Metalloprotein-Specific or Critical Amino Acid Residues: Perspectives on Plant-Precise Detoxification and Recognition Mechanisms under Cadmium Stress.International journal of molecular sciences · 2022Review
- Use of omics analysis for low-dose radiotoxicology and health risk assessment: the case of uranium.Environmental epigenetics · 2022Review
- Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Prenatal blood lead levels and reduced preadolescent glomerular filtration rate: Modification by body mass index.Environment international · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundEnvironmental chemical exposures have been implicated in pediatric kidney disease. No appraisal of the available evidence has been conducted on this topic.
methodsWe performed a systematic review of the epidemiologic studies that assessed association of environmental exposures with measures of kidney function and disease in pediatric populations. The search period went through July 2016.
resultsWe found 50 studies that met the search criteria and were included in this systematic review. Environmental exposures reviewed herein included lead, cadmium, mercury, arsenic, fluoride, aflatoxin, melamine, environmental tobacco, bisphenol A, dental procedures, phthalates, ferfluorooctanoic acid, triclosan, and thallium/uranium. Most studies assessed environmental chemical exposure via biomarkers but four studies assessed exposure via proximity to emission source. There was mixed evidence of association between metal exposures, and other non-metal environmental exposures and pediatric kidney disease and other kidney disease biomarkers. The evaluation of causality is hampered by the small numbers of studies for each type of environmental exposure, as well as lack of study quality and limited prospective evidence.
conclusionThere is a need for well-designed epidemiologic studies of environmental chemical exposures and kidney disease outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.