ArticleJournal of biomedical optics2017
Solid tissue simulating phantoms having absorption at 970 nm for diffuse optics.
Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Enhancing skin tone representation in optical vascular phantoms.Journal of biomedical optics · 2026Article
- Roadmap for light interaction with biophotonic surfaces and their diverse applications.Journal of biomedical optics · 2026Article
- Impact of the β correction factor on the accuracy of speckle contrast imaging measurements.Biomedical optics express · 2026Article
- Optical phantoms for the characterization and validation of imaging and spectroscopy: a review.Biophotonics discovery · 2026Review
- Human Skin Models in Biophotonics: Materials, Methods, and Applications.Advanced healthcare materials · 2025Review
- Direct 3-D printing of complex optical phantoms using dynamic filament mixing.Scientific reports · 2025Article
- Fabrication of complex optical phantoms using on-the-fly multi-filament mixing 3-D printing.Research square · 2024Article
- Multimodal optical imaging of the oculofacial region using a solid tissue-simulating facial phantom.Journal of biomedical optics · 2024Article
- Design and characterization of color printed polyurethane films as biomedical phantom layers.Biomedical optics express · 2023Article
- Tissue-mimicking phantom materials with tunable optical properties suitable for assessment of diffuse reflectance spectroscopy during electrosurgery.Biomedical optics express · 2022Article
- Water and hemoglobin modulated gelatin-based phantoms to spectrally mimic inflamed tissue in the validation of biomedical techniques and the modeling of microdialysis data.Journal of biomedical optics · 2022Article
- Spatial frequency domain imaging in 2019: principles, applications, and perspectives.Journal of biomedical optics · 2019Review
- Solid phantom recipe for diffuse optics in biophotonics applications: a step towards anatomically correct 3D tissue phantoms.Biomedical optics express · 2019Article
- Algorithm for rapid determination of optical scattering parameters.Optics express · 2017Article
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Authors and funding
6 authors.
Funding
Abstract
Tissue simulating phantoms can provide a valuable platform for quantitative evaluation of the performance of diffuse optical devices. While solid phantoms have been developed for applications related to characterizing exogenous fluorescence and intrinsic chromophores such as hemoglobin and melanin, we report the development of a poly(dimethylsiloxane) (PDMS) tissue phantom that mimics the spectral characteristics of tissue water. We have developed these phantoms to mimic different water fractions in tissue, with the purpose of testing new devices within the context of clinical applications such as burn wound triage. Compared to liquid phantoms, cured PDMS phantoms are easier to transport and use and have a longer usable life than gelatin-based phantoms. As silicone is hydrophobic, 9606 dye was used to mimic the optical absorption feature of water in the vicinity of 970 nm. Scattering properties are determined by adding titanium dioxide, which yields a wavelength-dependent scattering coefficient similar to that observed in tissue in the near-infrared. Phantom properties were characterized and validated using the techniques of inverse adding-doubling and spatial frequency domain imaging. Results presented here demonstrate that we can fabricate solid phantoms that can be used to simulate different water fractions
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