Evidence map›Paper›PMID 28727663›Full record

SynthesisJournal of addiction medicine

Mindfulness-based Relapse Prevention for Substance Use Disorders: A Systematic Review and Meta-analysis.

Sean Grant, Benjamin Colaiaco, Aneesa Motala, Roberta Shanman, Marika Booth, Melony Sorbero, Susanne Hempel

3 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 75 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06443294 naunknown statusnot on this map

Development of a Smoking Cessation Video Series

TypeinterventionalSponsorWayne State UniversityRan2024 to 2024Enrolled120ConditionsTobacco Use Cessation, Tobacco SmokingArmsSmoking cessation video series.
NCT06739304 nacompletednot on this map

The Effectiveness of Mindfulness-based Relapse Prevention: A Randomized Controlled Trial Study

TypeinterventionalSponsorSir Run Run Shaw HospitalRan2023 to 2023Enrolled1,200ConditionsSubstance Use DisorderArmsMindfulness-based Relapse Prevention
NCT07741825 narecruitingnot on this map

Adapting and Pilot Testing Mindfulness-Based Relapse Prevention for Substance Use Peer Workers

TypeinterventionalSponsorUniversity of Texas at AustinRan2026 to 2030Enrolled80ConditionsRelapse/Recurrence, Substance Use (Drugs, Alcohol), BurnoutArmsMindfulness Based Relapse Prevention, Standard of Care
3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  7. Mindfulness-based interventions for substance use disorders.The Cochrane database of systematic reviews · 2021
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sean GrantRAND Corporation, Santa Monica, CA (S.G., B.C., A.M., R.S., M.B., S.H.); and RAND Corporation, Pittsburgh, PA (M.S.).
Benjamin Colaiaco
Aneesa Motala
Roberta Shanman
Marika Booth
Melony Sorbero
Susanne Hempel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSubstance use disorder (SUD) is a prevalent health issue with serious personal and societal consequences. This review aims to estimate the effects and safety of Mindfulness-based Relapse Prevention (MBRP) for SUDs.

methodsWe searched electronic databases for randomized controlled trials evaluating MBRP for adult patients diagnosed with SUDs. Two reviewers independently assessed citations, extracted trial data, and assessed risks of bias. We conducted random-effects meta-analyses and assessed quality of the body of evidence (QoE) using the Grading of Recommendations Assessment, Development, and Evaluation approach.

resultsWe identified 9 randomized controlled trials comprising 901 participants. We did not detect statistically significant differences between MBRP and comparators on relapse (odds ratio [OR] 0.72, 95% confidence interval [CI] 0.46-1.13, low QoE), frequency of use (standardized mean difference [SMD] 0.02, 95% CI -0.40 to 0.44, low QoE), treatment dropout (OR 0.81, 95% CI 0.40 to 1.62, very low QoE), depressive symptoms (SMD -0.09, 95% CI -0.39 to 0.21, low QoE), anxiety symptoms (SMD -0.32, 95% CI -1.16 to 0.52, very low QoE), and mindfulness (SMD -0.28, 95% CI -0.72 to 0.16, very low QoE). We identified significant differences in favor of MBRP on withdrawal/craving symptoms (SMD -0.13, 95% CI -0.19 to -0.08, I = 0%, low QoE) and negative consequences of substance use (SMD -0.23, 95% CI -0.39 to -0.07, I = 0%, low QoE). We found negligible evidence of adverse events.

conclusionsWe have limited confidence in estimates suggesting MBRP yields small effects on withdrawal/craving and negative consequences versus comparator interventions. We did not detect differences for any other outcome. Future trials should aim to minimize participant attrition to improve confidence in effect estimates.

Indexed as

HumansMindfulnessOutcome Assessment, Health CareSecondary PreventionSubstance-Related Disorders

Identifiers

PMID28727663
PMCPMC5636047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.