Trial reportCancer nursing
Physical Activity and Survival in Women With Advanced Breast Cancer.
Trial report in Cancer nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- The effects of aerobic and resistance training across eight cancer types: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Impact of Lifestyle Modifications on Cancer Mortality: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Resistance training for depression: a systematic review and meta-analysis of randomized controlled trials.Frontiers in psychology · 2025Pooled it
- Effects of exercise interventions on breast cancer-related endogenous hormones in premenopausal and postmenopausal women: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Postdiagnosis recreational physical activity and breast cancer prognosis: Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis.International journal of cancer · 2023Pooled it
- The lasting effects of resistance and endurance exercise interventions on breast cancer patient mental wellbeing and physical fitness.Scientific reports · 2022Pooled it
- Effects of physical activity on sleep problems in breast cancer survivors: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- The effects of physical activity on overall survival among advanced cancer patients: a systematic review and meta-analysis.BMC cancer · 2021Pooled it
- Feasibility and preliminary effects of the Fit2ThriveMB pilot physical activity promotion intervention on physical activity and patient reported outcomes in individuals with metastatic breast cancer.Breast cancer research and treatment · 2024Trial
- Effects of combined exercises on shoulder mobility and strength of the upper extremities in breast cancer rehabilitation: a 3-week randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Trial
- Factors Associated with Meeting Physical Activity Guideline Recommendations in a Single Community Rehabilitation Center in Singapore: An Exploratory Study.Healthcare (Basel, Switzerland) · 2026Article
- Biological basis and clinical translation prospects of circulating cell-free DNA in precision management of breast cancer (Review).Oncology letters · 2026Review
- Outcomes for breast cancer survivors with metastatic disease in a physical activity program for medically underserved cancer survivors.Journal of cancer survivorship : research and practice · 2025Article
- Exercise Prescription in Cardio-Oncology.Journal of clinical medicine · 2025Review
- Assessment of the functional and health-related needs of patients with metastatic breast cancer prior to initiation of cancer treatment.Breast cancer research and treatment · 2025Article
- Neutrophil-to-lymphocyte ratio is associated with accelerometer-measured physical activity levels in breast cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Charting cancer's course: revealing the role of diet, exercise, and the microbiome in cancer evolution and immunotherapy response.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Review
- Impact of combiner aerobic and resistance training on depression: a systematic review and meta-analysis of randomized controlled trials.BMC sports science, medicine & rehabilitation · 2025Article
- Management of cancer treatment-related fatigue in advanced breast cancer patients: an expert committee's opinion.Frontiers in oncology · 2025Review
- The impact of physical activity on progression-free and overall survival in metastatic breast cancer based on molecular subtype.BMC cancer · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundSeveral empirical investigations have attempted to characterize the effect of physical activity on cancer mortality, but these investigations have rarely focused on patients with advanced breast cancer.
objectiveThe current study examined the hypothesis that greater physical activity is associated with longer survival among women with advanced breast cancer.
methodsWe conducted a secondary data analysis of a prospective study of 103 patients with stage IV (n = 100) or locally recurrent (n = 3) breast cancer involved in a group psychotherapy trial. Physical activity was assessed at baseline using the Seven-Day Physical Activity Recall questionnaire, and patients were followed until April 1, 2016, at which time 93 of 103 had died.
resultsGreater physical activity level at baseline was significantly associated with longer subsequent survival time in a Cox proportional hazards model (hazard ratio [HR], 0.90; 95% confidence interval [CI], 0.84-0.97; P < .01). Engaging in 1 additional hour per day of moderate activity reduced the hazard of subsequent mortality by 23% (HR, 0.77; 95% CI, 0.65-0.92; P < .01). These results remained significant even after controlling for demographic, medical, cancer, depression, and cortisol variables (HR, 0.91; 95% CI, 0.84-0.99; P < .05).
conclusionsWomen with advanced breast cancer who engaged in physical activity for 1 or more hours per day at baseline had an increased likelihood of survival compared with those who exercised less than 1 hour per day. IMPLICATIONS FOR PRACTICE: Nurses should consider recommending moderate physical activity for women with advanced breast cancer. Randomized trials of physical activity interventions for this population are needed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.