ReviewVector borne and zoonotic diseases (Larchmont, N.Y.)2017
Brave New Worlds: The Expanding Universe of Lyme Disease.
Review in Vector borne and zoonotic diseases (Larchmont, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 2 syntheses or guidelines pooled it, 138 citations in OpenAlex.
- A systematic review of the effectiveness and utility of Lyme disease prevention measures in Canada, the United States, and Europe.BMC infectious diseases · 2025Pooled it
- A scoping review of knowledge, attitudes, and practices in swine farm biosecurity in North America.Frontiers in veterinary science · 2025Pooled it
- Molecular detection of relapsing fevermSphere · 2026Article
- A deformylase inhibitor expands therapeutic options for Lyme disease.Research square · 2026Article
- Prevalence and Risk Factors ofPathogens (Basel, Switzerland) · 2026Article
- Relapsing feverbioRxiv : the preprint server for biology · 2026Article
- UnmaskingInternational journal for parasitology. Parasites and wildlife · 2025Review
- Harnessing 50 years of tick population genetics: Choosing the right molecular tool for contemporary research.The Journal of animal ecology · 2025Review
- A Lyme disease mRNA vaccine targetingMolecular therapy. Nucleic acids · 2025Article
- Using pet insurance claims to predict occurrence of vector-borne and zoonotic disease in humans in the United States.Scientific reports · 2025Article
- Article
- Lactate dehydrogenase is the Achilles' heel of Lyme disease bacteriumbioRxiv : the preprint server for biology · 2025Article
- Exploring the safety and immunogenicity of the VLA15 vaccine among healthy or high-risk population: a systematic review and meta-analysis of randomized controlled trials.Therapeutic advances in vaccines and immunotherapy · 2025Review
- Do white-footed mice, the main reservoir of the Lyme disease pathogen in the United States, clinically respond to the borrelial tenancy?Infection and immunity · 2024Article
- Lyme Disease Under-Ascertainment During the COVID-19 Pandemic in the United States: Retrospective Study.JMIR public health and surveillance · 2024Article
- Changes in the Transcriptome and Long Non-Coding RNAs but Not the Methylome Occur in Human Cells Exposed toGenes · 2024Article
- Assessing the value and knowledge gains from an online tick identification and tick-borne disease management course for the Southeastern United States.BMC public health · 2024Article
- A sex-based analysis of complete blood count features during acute, untreated Lyme disease.Frontiers in medicine · 2024Article
- Synergistic integration of climate change and zoonotic diseases by artificial intelligence: a holistic approach for sustainable solutions.Science in One Health · 2024Article
- Identification of habitat suitability for the dominant zoonotic tick speciesScience in One Health · 2024Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Projections around the globe suggest an increase in tick-vectored disease incidence and distribution, and the potential for emergence of novel tick-borne pathogens. Lyme disease is the most common reported tick-borne illness in the Unites States and is prevalent throughout much of central Europe. In recent years, the worldwide burden of Lyme disease has increased and extended into regions and countries where the disease was not previously reported. In this review, we discuss the trends for increasing Lyme disease, and examine the factors driving Lyme disease expansion, including the effect of climate change on the spread of vector Ixodid ticks and reservoir hosts; and the impacts of increased awareness on disease reporting and diagnosis. To understand the growing threat of Lyme disease, we need to study the interplay between vector, reservoir, and pathogen. In addition, we need to understand the contributions of climate conditions to changes in disease risk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.