Evidence map›Paper›PMID 28727203›Full record

ArticleJournal of cardiovascular electrophysiology2017

The association between acute mental stress and abnormal left atrial electrophysiology.

Wesley T O'Neal, Muhammad Hammadah, Pratik B Sandesara, Zakaria Almuwaqqat, Ayman Samman-Tahhan, Mohamad M Gafeer, Naser Abdelhadi, Kobina Wilmot, Ibhar Al Mheid, Douglas J Bremner and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Review
  5. The Impact of War-Related Stress on Coronary Artery Disease Severity in War Survivors: A SYNTAX Study.International journal of environmental research and public health · 2021
    Article
  6. Article
  7. Article
  8. Observational
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Wesley T O'NealDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.ORCID http://orcid.org/0000-0003-0751-4760
Muhammad HammadahDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Pratik B SandesaraDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Zakaria AlmuwaqqatDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Ayman Samman-TahhanDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Mohamad M GafeerDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Naser AbdelhadiDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Kobina WilmotDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Ibhar Al MheidDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Douglas J BremnerDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Michael KutnerDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Elsayed Z SolimanDepartment of Internal Medicine, Section on Cardiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Amit J ShahDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Arshed A QuyyumiDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Viola VaccarinoDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · USWake Forest University · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Vascular Responses During Mental StressP01HL101398 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2010 to 2015
$11.0M
Mental Stress and Myocardial Ischemia after MI: Sex Differences, Mechanisms and PrognosisR01HL109413 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2012 to 2023
$6.9M
Neural Circuits in Women with Abuse and PTSDR01MH056120 · NIMH · YALE UNIVERSITY · PI BREMNER, JAMES DOUGLAS · 1999 to 2011
$5.0M
PTSD and Ischemic Heart Disease Progression: A Longitudinal Twin StudyR01HL125246 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2015 to 2018
$3.4M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalKL2TR000455 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$2.9M
Mechanisms of Depression in CVDR01HL088726 · NHLBI · EMORY UNIVERSITY · PI BREMNER, JAMES DOUGLAS · 2008 to 2012
$2.6M
Mind-Body Interactions in Cardiovascular DiseaseK24HL077506 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2004 to 2013
$1.5M
Biological Correlates of Traumatic StressK24MH076955 · NIMH · EMORY UNIVERSITY · PI BREMNER, JAMES DOUGLAS · 2006 to 2013
$946k
The Association between Acute Mental Stress and Electrocardiographic Left Atrial AbnormalitiesF32HL134290 · NHLBI · EMORY UNIVERSITY · PI O'NEAL, WESLEY T · 2016 to 2017
$122k
NCATS NIH HHS KL2 TR000455NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR002378NHLBI NIH HHS F32 HL134290NHLBI NIH HHS K24 HL077506NHLBI NIH HHS P01 HL101398NHLBI NIH HHS R01 HL088726NHLBI NIH HHS R01 HL109413NHLBI NIH HHS R01 HL125246NIMH NIH HHS K24 MH076955NIMH NIH HHS R01 MH056120
6 · The paper itself

Abstract

backgroundAcute stress may trigger atrial fibrillation (AF), but the underlying mechanisms are unclear. We examined if acute mental stress results in abnormal left atrial electrophysiology as detected by more negative deflection of P-wave terminal force in lead V METHODS AND

resultsWe examined this hypothesis in 422 patients (mean age = 56 ± 10 years; 61% men; 44% white) with stable coronary heart disease who underwent mental (speech task) stress testing. PTFV

conclusionAcute mental stress alters left atrial electrophysiology, suggesting that stressful situations promote adverse transient electrical changes to provide the necessary substrate for AF.

Indexed as

Electrophysiological PhenomenaAdultAgedAged, 80 and overAtrial FibrillationCardiac ElectrophysiologyCoronary DiseaseElectrocardiographyFemaleHeart AtriaHumansMaleMiddle AgedRisk AssessmentStress, Psychologicalarrhythmiaelectrocardiogramelectrophysiologyleft atrial abnormalitymental stress

Identifiers

PMID28727203
PMCPMC5638698
OpenAlexW2738352555

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.