Evidence map›Paper›PMID 28727159›Full record

ArticleAlcoholism, clinical and experimental research2017

Children with Heavy Prenatal Alcohol Exposure Exhibit Atypical Gait Characteristics.

Tenille C Taggart, Roger W Simmons, Jennifer D Thomas, Edward P Riley

Abstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Spiral drawing deficits in children with prenatal alcohol exposure.Alcohol, clinical & experimental research · 2023
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tenille C TaggartCenter for Behavioral Teratology , Department of Psychology, San Diego State University, San Diego, California.
Roger W SimmonsMotor Control Laboratory , School of Exercise and Nutritional Sciences, San Diego State University, San Diego, California.ORCID http://orcid.org/0000-0002-1718-8877
Jennifer D ThomasCenter for Behavioral Teratology , Department of Psychology, San Diego State University, San Diego, California.
Edward P RileyCenter for Behavioral Teratology , Department of Psychology, San Diego State University, San Diego, California.

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN M. SMITH · 1999 to 2026
$31.6M
Cross-Cultural Assessment of FASDU24AA014811 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY · 2003 to 2026
$13.1M
Regulation of Force in Children with Prenatal Exposure to AlcoholR21AA017256 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI SIMMONS, ROGER WILLIAM · 2009 to 2010
$409k
NIAAA NIH HHS R21 AA017256NIAAA NIH HHS U24 AA014811NIDDK NIH HHS P30 DK056350
6 · The paper itself

Abstract

backgroundImpaired motor function in children with histories of prenatal exposure to alcohol has been previously reported but, to date, no studies using quantitatively based analyses have been performed to assess gait in these children.

methodsGait of children with (n = 18) or without (n = 26) prenatal alcohol exposure was assessed using an electronically instrumented walkway. Children completed blocks of trials traversing the walkway with different combinations of walking condition (increased, self-paced, and decreased cadence) and direction (forward and backward). Gait velocity, cadence, stride length, step width, foot angle, and double support time, as well as the variability of these temporal-spatial markers, were used to assess gait.

resultsResults indicated that, in comparison with typically developing children, alcohol-exposed children produced exaggerated foot angle and increased step width. Additionally, alcohol-exposed children produced greater intrasubject variability of gait velocity and walking cadence while walking forward and backward, and greater variability in step width when walking backward and for all 3 walking conditions.

conclusionsThe results indicate that selected gait markers are adversely affected by prenatal exposure to alcohol. Clinicians and front-line personnel (e.g., teachers) should provide movement enriched experiences to help ameliorate these alcohol-related deficits.

Indexed as

Biomechanical PhenomenaCentral Nervous System DepressantsChildEthanolFemaleFetal Alcohol Spectrum DisordersFootGaitGait Disorders, NeurologicHumansIndividualityMalePregnancyPrenatal Exposure Delayed EffectsCentral Nervous System DepressantsEthanolFetal Alcohol Spectrum DisorderGaitGAITrite®Teratogenesis

Identifiers

PMID28727159
PMCPMC5581268

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.