Evidence map›Paper›PMID 28726912›Full record

ArticleLab on a chip2017

3D material cytometry (3DMaC): a very high-replicate, high-throughput analytical method using microfabricated, shape-specific, cell-material niches.

Kirsten Parratt, Jenny Jeong, Peng Qiu, Krishnendu Roy

Abstract read
In one paragraph

Article in Lab on a chip, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kirsten ParrattSchool of Materials Science and Engineering, Georgia Institute of Technology, 30332, USA.
Jenny Jeong
Peng Qiu
Krishnendu Roy

Funding

Identifying the cellular hierarchy and drug response of AML using cytometric dataR01CA163481 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI QIU, PENG · 2012 to 2015
$1.1M
NCI NIH HHS R01 CA163481
6 · The paper itself

Abstract

Studying cell behavior within 3D material niches is key to understanding cell biology in health and diseases, and developing biomaterials for regenerative medicine applications. Current approaches to studying these cell-material niches have low throughput and can only analyze a few replicates per experiment resulting in reduced measurement assurance and analytical power. Here, we report 3D material cytometry (3DMaC), a novel high-throughput method based on microfabricated, shape-specific 3D cell-material niches and imaging cytometry. 3DMaC achieves rapid and highly multiplexed analyses of very high replicate numbers ("n" of 10

Indexed as

AnimalsBiocompatible MaterialsCell LineCell SurvivalCellular MicroenvironmentCytological TechniquesEquipment DesignHigh-Throughput Screening AssaysHumansHydrogelsMiceMicrofluidic Analytical TechniquesBiocompatible MaterialsHydrogels

Identifiers

PMID28726912
PMCPMC5577978

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.