ArticleNature2017
Ribosomes are optimized for autocatalytic production.
Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed.
- Effect of transcriptional delay on ribosome abundance control.Journal of mathematical biology · 2026Article
- Remodelled ribosomal populations synthesize a specific proteome in proliferating plant tissue during cold.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Metabolic engineering of yeast to efficiently synthesize heme and hemoproteins: recent advance and prospects.FEMS yeast research · 2025Review
- The proteome is a terminal electron acceptor.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Metabolic rearrangement enables adaptation of microbial growth rate to temperature shifts.Nature microbiology · 2025Article
- A framework for understanding collective microbiome metabolism.Nature microbiology · 2024Review
- Costs of ribosomal RNA stabilization affect ribosome composition at maximum growth rate.Communications biology · 2024Article
- Opinion: The Key Steps in the Origin of Life to the Formation of the Eukaryotic Cell.Life (Basel, Switzerland) · 2024Review
- From the RNA-Peptide World: Prebiotic Reaction Conditions Compatible with Lipid Membranes for the Formation of Lipophilic Random Peptides in the Presence of Short Oligonucleotides, and More.Life (Basel, Switzerland) · 2024Article
- Article
- Substantial rDNA copy number reductions alter timing of development and produce variable tissue-specific phenotypes in C. elegans.Genetics · 2023Article
- Article
- Optimization of ribosome utilization inPNAS nexus · 2023Article
- Role of main RNA modifications in cancer: NSignal transduction and targeted therapy · 2022Review
- Supramolecular assembly of protein building blocks: from folding to function.Nano convergence · 2022Review
- Article
- Fundamental limits on the rate of bacterial growth and their influence on proteomic composition.Cell systems · 2021Article
- Emergent Damped Oscillation Induced by Nutrient-Modulating Growth Feedback.ACS synthetic biology · 2021Article
- Prebiotic Pathway from Ribose to RNA Formation.International journal of molecular sciences · 2021Review
- Exploring the effect of network topology, mRNA and protein dynamics on gene regulatory network stability.Nature communications · 2021Article
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3 authors.
Funding
Abstract
Many fine-scale features of ribosomes have been explained in terms of function, revealing a molecular machine that is optimized for error-correction, speed and control. Here we demonstrate mathematically that many less well understood, larger-scale features of ribosomes-such as why a few ribosomal RNA molecules dominate the mass and why the ribosomal protein content is divided into 55-80 small, similarly sized segments-speed up their autocatalytic production.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.