Evidence map›Paper›PMID 28726642›Full record

ArticleThe Journal of biological chemistry2017

Coordinated transcriptional control of adipocyte triglyceride lipase (

Debasish Roy, Kenneth T Farabaugh, Jing Wu, Alyssa Charrier, Cynthia Smas, Maria Hatzoglou, Kavitha Thirumurugan, David A Buchner

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Caspase-6 Controls Lipid and Energy Metabolism in Diet-Induced Obesity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Debasish RoyFrom the School of Biosciences and Technology, VIT University, Tamil Nadu 632014, India.
Kenneth T Farabaughthe Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio 44106, and.
Jing Wuthe Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio 44106, and.
Alyssa Charrierthe Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio 44106, and.
Cynthia Smasthe Department of Biochemistry and Cancer Biology, University of Toledo College of Medicine, Toledo, Ohio 43614.
Maria Hatzoglouthe Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio 44106, and mxh8@case.edu.
Kavitha ThirumuruganFrom the School of Biosciences and Technology, VIT University, Tamil Nadu 632014, India, m.kavitha@vit.ac.in.
David A Buchnerthe Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio 44106, and.
Case Western Reserve University · USVellore Institute of Technology University · INUniversity of Toledo · US

Funding

Regulation of Gene Expression During StressR01DK053307 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI HATZOGLOU, MARIA · 1998 to 2021
$9.6M
GRADUATE TRAINING IN CELLULAR AND MOLECULAR BIOLOGYT32GM008056 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI DIEHL, JOHN ALAN, SNIDER, MARTIN D · 1985 to 2019
$7.1M
Translational Control by Osmotically Active SolutesR37DK060596 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI HATZOGLOU, MARIA · 2011 to 2020
$5.3M
Epistatic Regulation of Gene ExpressionR03DK099533 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI BUCHNER, DAVID A · 2014 to 2015
$159k
NIDDK NIH HHS R01 DK053307NIDDK NIH HHS R03 DK099533NIDDK NIH HHS R37 DK060596NIGMS NIH HHS T32 GM008056
6 · The paper itself

Abstract

The breakdown of stored fat deposits into its components is a highly regulated process that maintains plasma levels of free fatty acids to supply energy to cells. Insulin-mediated transcription of

Indexed as

Transcription, Genetic3T3-L1 CellsAdipocytesAdipogenesisAnimalsCell LineDown-RegulationHEK293 CellsHumansLipaseMiceMice, Inbred C57BLMutagenesis, Site-DirectedPPAR gammaSp1 Transcription FactorLipasePPAR gammaSp1 Transcription Factoradipogenesisadipose triglyceride lipase (ATGL)gene regulationperoxisome proliferator–activated receptor (PPAR)specificity protein 1 (Sp1)

Identifiers

PMID28726642
PMCPMC5592664
OpenAlexW2737662761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.