Evidence map›Paper›PMID 28726632›Full record

ArticleeLife2017

Dynamics of genomic innovation in the unicellular ancestry of animals.

Xavier Grau-Bové, Guifré Torruella, Stuart Donachie, Hiroshi Suga, Guy Leonard, Thomas A Richards, Iñaki Ruiz-Trillo

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Diversity and spatial segregation of TRP channels in the closest relatives of animals.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  14. The life cycle of type IV collagen.Matrix biology : journal of the International Society for Matrix Biology · 2025
    Review
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  20. Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xavier Grau-BovéInstitut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Barcelona, Catalonia, Spain.ORCID 0000-0003-1978-5824
Guifré TorruellaUnité d'Ecologie, Systématique et Evolution, Université Paris-Sud/Paris-Saclay, AgroParisTech, Orsay, France.ORCID 0000-0002-6534-4758
Stuart DonachieDepartment of Microbiology, University of Hawai'i at Mānoa, Honolulu, United States.
Hiroshi SugaFaculty of Life and Environmental Sciences, Prefectural University of Hiroshima, Hiroshima, Japan.
Guy LeonardDepartment of Biosciences, University of Exeter, Exeter, United Kingdom.
Thomas A RichardsDepartment of Biosciences, University of Exeter, Exeter, United Kingdom.ORCID 0000-0002-6096-750X
Iñaki Ruiz-TrilloInstitut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Barcelona, Catalonia, Spain.ORCID 0000-0001-6547-5304

Funding

European Research Council 616960
6 · The paper itself

Abstract

Which genomic innovations underpinned the origin of multicellular animals is still an open debate. Here, we investigate this question by reconstructing the genome architecture and gene family diversity of ancestral premetazoans, aiming to date the emergence of animal-like traits. Our comparative analysis involves genomes from animals and their closest unicellular relatives (the Holozoa), including four new genomes: three Ichthyosporea and

Indexed as

Evolution, MolecularGenome, ProtozoanEukaryotaGenomicsanimal originschromosomescomparative genomicsevolutionary biologygene family evolutiongenesgenomicsholozoansichthyosporeansintrons

Identifiers

PMID28726632
PMCPMC5560861

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.