Evidence map›Paper›PMID 28726545›Full record

ArticleRNA biology2018

The t

Jo Marie Bacusmo, Silvia S Orsini, Jennifer Hu, Michael DeMott, Patrick C Thiaville, Ameer Elfarash, Mellie June Paulines, Diego Rojas-Benítez, Birthe Meineke, Chris Deutsch and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Compendium of RNA modifications for bacterial stress adaptation.Microbiology and molecular biology reviews : MMBR · 2026
    Review
  2. Epigenomics identifies three sources of DNA methylation inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Specificity and mechanism of tRNA cleavage by the AriB Toprim nuclease of the PARIS bacterial immune system.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Naturally occurring modified ribonucleosides.Wiley interdisciplinary reviews. RNA · 2020
    Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Jo Marie Bacusmoa Department of Microbiology and Cell Science, IFAS , University of Florida , Gainesville , FL , USA.ORCID 0000-0003-1021-1824
Silvia S Orsinia Department of Microbiology and Cell Science, IFAS , University of Florida , Gainesville , FL , USA.
Jennifer Hub Center for Environmental Health Sciences, Department of Biological Engineering , Massachusetts Institute of Technology , Cambridge , MA , USA.
Michael DeMottb Center for Environmental Health Sciences, Department of Biological Engineering , Massachusetts Institute of Technology , Cambridge , MA , USA.
Patrick C Thiavillea Department of Microbiology and Cell Science, IFAS , University of Florida , Gainesville , FL , USA.
Ameer Elfarasha Department of Microbiology and Cell Science, IFAS , University of Florida , Gainesville , FL , USA.
Mellie June Paulinesf Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry , University of Cincinnati , Cincinnati OH , USA.
Diego Rojas-Benítezg Centro de Regulación del Genoma. Facultad de Ciencias - Universidad de Chile , Santiago , Chile.
Birthe Meinekeh Molecular Biology Program , Sloan-Kettering Institute , New York , NY , USA.
Chris Deutschi Department of Chemistry , Portland State University , Portland , OR , USA.
Dirk Iwata-Reuyli Department of Chemistry , Portland State University , Portland , OR , USA.
Patrick A Limbachf Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry , University of Cincinnati , Cincinnati OH , USA.
Peter C Dedonb Center for Environmental Health Sciences, Department of Biological Engineering , Massachusetts Institute of Technology , Cambridge , MA , USA.
Kelly C Ricea Department of Microbiology and Cell Science, IFAS , University of Florida , Gainesville , FL , USA.ORCID 0000-0003-1335-4409
Stewart Shumanh Molecular Biology Program , Sloan-Kettering Institute , New York , NY , USA.
Valérie de Crécy-Lagarda Department of Microbiology and Cell Science, IFAS , University of Florida , Gainesville , FL , USA.
University of Florida · USCenter for Environmental Health · USKettering University · USPortland State University · USUniversity of Cincinnati · USUniversity of Chile · CL

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LEVINE, STUART S · 1985 to 2020
$25.6M
TRAINING GRANTS IN ENVIROMENTAL TOXICOLOGYT32ES007020 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ESSIGMANN, JOHN M · 1985 to 2024
$13.1M
Viral RNA Modifying EnzymesR01GM042498 · NIGMS · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SHUMAN, STEWART H · 1989 to 2017
$6.8M
Regulation of Staphylococcus aureus physiology by bacterial nitric oxideR01AI118999 · NIAID · UNIVERSITY OF FLORIDA · PI RICE, KELLY CHRISTINE · 2016 to 2020
$1.7M
NCI NIH HHS P30 CA008748NIAID NIH HHS R01 AI118999NIEHS NIH HHS P30 ES002109NIEHS NIH HHS T32 ES007020NIGMS NIH HHS R01 GM042498
6 · The paper itself

Abstract

Endoribonuclease toxins (ribotoxins) are produced by bacteria and fungi to respond to stress, eliminate non-self competitor species, or interdict virus infection. PrrC is a bacterial ribotoxin that targets and cleaves tRNA

Indexed as

RNA Processing, Post-TranscriptionalAdenosineAnticodonBacterial ProteinsBacterial ToxinsEndoribonucleasesEscherichia coliNucleic Acid ConformationProtein BiosynthesisRNA, Transfer, LysStreptococcus mutansAdenosineAnticodonBacterial ProteinsBacterial ToxinsEndoribonucleasesN(6)-(N-threonylcarbonyl)adenosineRNA, Transfer, LysModified nucleosidesRNA maturationt6A detectiontranslation

Identifiers

PMID28726545
PMCPMC6103680
OpenAlexW2739015053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.