Evidence map›Paper›PMID 28726541›Full record

ArticleMolecular pain

Characterization of postsynaptic calcium signals in the pyramidal neurons of anterior cingulate cortex.

Xu-Hui Li, Qian Song, Tao Chen, Min Zhuo

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Enhanced long-term potentiation in the anterior cingulate cortex of tree shrew.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Article
  6. Article
  7. Review
  8. Altered miRNA landscape of the anterior cingulate cortex is associated with potential loss of key neuronal functions in depressed brain.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2020
    Article
  9. Neuronal Adenylyl Cyclase Targeting Central Plasticity for the Treatment of Chronic Pain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020
    Review
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Xu-Hui Li1 Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Qian Song1 Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Tao Chen1 Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Min Zhuo1 Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Xi'an Jiaotong University · CNUniversity of Toronto · CA

Funding

CIHR MOP-124807
6 · The paper itself

Abstract

Calcium signaling is critical for synaptic transmission and plasticity. N-methyl-D-aspartic acid (NMDA) receptors play a key role in synaptic potentiation in the anterior cingulate cortex. Most previous studies of calcium signaling focus on hippocampal neurons, little is known about the activity-induced calcium signals in the anterior cingulate cortex. In the present study, we show that NMDA receptor-mediated postsynaptic calcium signals induced by different synaptic stimulation in anterior cingulate cortex pyramidal neurons. Single and multi-action potentials evoked significant suprathreshold Ca

Indexed as

Calcium SignalingAction PotentialsAnimalsCalcium ChannelsElectric StimulationGlutamic AcidGyrus CinguliLong-Term PotentiationMaleMice, Inbred C57BLPyramidal CellsReceptors, N-Methyl-D-AspartateSynapsesCalcium ChannelsGlutamic AcidReceptors, N-Methyl-D-Aspartateanterior cingulate cortexcalcium imaginglong-term potentiationNMDA receptorsSynaptic plasticitytwo-photon microscopy

Identifiers

PMID28726541
PMCPMC5524231
OpenAlexW2737369184

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.