Trial reportSurgical endoscopy2018
First human use of hybrid synthetic/biologic mesh in ventral hernia repair: a multicenter trial.
Trial report in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- A scoping review of outcome reporting in randomized controlled trials of incisional and non-incisional ventral hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Patient and clinical factors associated with postoperative follow-up duration after ventral hernia repair: a single-center retrospective study.Surgical endoscopy · 2025Article
- Innovative Strategies in Hernia Mesh Design: Materials, Mechanics, and Modeling.Materials (Basel, Switzerland) · 2025Review
- Combined use of composite mesh and acellular dermal matrix graft for abdominal wall repair following tumour resection.World journal of surgical oncology · 2024Article
- Maximizing mesh mileage: evaluating the long-term performance of a novel hybrid mesh for ventral hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- Evaluation of long-term performance of an intraperitoneal biomaterial in the treatment of ventral hernias.Surgical endoscopy · 2023Article
- Outcomes of Biosynthetic and Synthetic Mesh in Ventral Hernia Repair.Plastic and reconstructive surgery. Global open · 2022Article
- Quality of life and surgical outcomes of robotic retromuscular ventral hernia repair using a new hybrid mesh reinforcement.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- The use of a novel synthetic resorbable scaffold (TIGR MatrixHernia : the journal of hernias and abdominal wall surgery · 2022Article
- Fascinating history of groin hernias: Comprehensive recognition of anatomy, classic considerations for herniorrhaphy, and current controversies in hernioplasty.World journal of methodology · 2021Review
- Polymer Hernia Repair Materials: Adapting to Patient Needs and Surgical Techniques.Materials (Basel, Switzerland) · 2021Review
- Contamination of hybrid hernia meshes compared to bioresorbable Phasix™ Mesh in a rabbit subcutaneous implant inoculation model.Annals of medicine and surgery (2012) · 2019Article
- Ultrasound shear wave elastography effectively predicts integrity of ventral hernia repair using acellular dermal matrix augmented with platelet-rich plasma (PRP).Surgical endoscopy · 2019Article
- Comparison of Hybrid Versus Synthetic Mesh in Robotic Rives-Stoppa Ventral Hernia Repair.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMesh options for reinforcement of ventral/incisional hernia (VIH) repair include synthetic or biologic materials. While each material has known advantages and disadvantages, little is understood about outcomes when these materials are used in combination. This multicenter study reports on the first human use of a novel synthetic/biologic hybrid mesh (Zenapro
methodsThis prospective, multicenter post-market clinical trial enrolled consecutive adults who underwent elective VIH repair with hybrid mesh placed in the intraperitoneal or retromuscular/preperitoneal position. Patients were classified as Ventral Hernia Working Group (VHWG) grades 1-3 and had clean or clean-contaminated wounds. Outcomes of ventral and incisional hernia were compared using appropriate parametric tests.
resultsIn all, 63 patients underwent VIH repair with hybrid mesh. Most were females (54.0%), had a mean age of 54.8 ± 10.9 years and mean body mass index of 34.5 ± 7.8 kg/m
conclusionZenapro
Indexed as
Identifiers
28726148What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.