ArticleEuropean radiology2018
Epidural steroid injection-related events requiring hospitalisation or emergency room visits among 52,935 procedures performed at a single centre.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Ultrasound-Guided Transforaminal Injections of Platelet-Rich Plasma Compared with Steroid in Lumbar Disc Herniation: A Prospective, Randomized, Controlled Study.Neural plasticity · 2021Trial
- Risk of ischemic and hemorrhagic complications associated with continuation versus interruption of antithrombotic therapy for cervical transforaminal injections: A retrospective study.Interventional pain medicine · 2026Article
- Complications during lumbar selective nerve root block: a scoping review.Acta neurochirurgica · 2025Article
- Factfinders for patient safety: Epidural steroid injection in patients with lumbar spinal stenosis.Interventional pain medicine · 2024Article
- Diagnosis and management of infections related to spinal pain interventions.Anesthesia and pain medicine · 2024Review
- Post-Discectomy Infection: A Critical Review and Suggestion of a Management Algorithm.Journal of clinical medicine · 2024Review
- FactFinders for patient safety: Delaying epidural steroid injections: Infection and safe platelet cutoff.Interventional pain medicine · 2024Article
- Interlaminar versus transforaminal epidural steroid injections: a review of efficacy and safety.Skeletal radiology · 2023Review
- Comparative Effectiveness of Epidural Steroid İnjections in Patients With Disc Bulging and Disc Protrusion.Cureus · 2023Article
- Clinical features and outcome of vertebral osteomyelitis after spinal injection: is it worth the price?Infection · 2023Article
- [Research progress of platelet-rich plasma in treatment of discogenic low back pain].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023Article
- Interventional Pain Procedures: A Narrative Review Focusing on Safety and Complications. Part 1 Injections for Spinal Pain.Journal of pain research · 2023Review
- Lumbar Spinal Steroid Injections and Infection Risk after Spinal Surgery: A Systematic Review and Meta-Analysis.Asian spine journal · 2022Article
- Article
- The skeletal consequences of epidural steroid injections: a literature review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Review
- Safety of epidural steroids: a review.Anesthesia and pain medicine · 2021Article
- Comparison of interlaminar CT-guided epidural platelet-rich plasma versus steroid injection in patients with lumbar radicular pain.European radiology · 2020Article
- Value of ultrasound-guided transforaminal nerve block in the treatment of lumbar disc herniation.The Journal of international medical research · 2020Article
- Intra-articular facet joint steroid injection-related adverse events encountered during 11,980 procedures.European radiology · 2020Article
- Clinical and imaging characteristics of patients with extreme low back pain or sciatica referred for spinal injection.Neuroradiology · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo analyse the incidence and type of epidural steroid injection (ESI)-related adverse events, including procedure-related complications and drug-related systemic effects requiring hospitalisation or emergency room (ER) visits.
methodsThis study included 52,935 ESI procedures performed in 22,059 patients in our department from March 2004 to February 2016. Of these, we retrospectively reviewed the cases of 1570 patients (1713 procedures) who were hospitalised or visited the ER within 1 month after ESI. ESI-related events were classified as procedure-related complications, drug-related systemic effects, or of uncertain relationship. Descriptive data are provided; no statistical analysis was performed.
resultsThere were 244 ESI-related events in 235 patients (males:females = 102:133; mean age: 65.7 years; range: 20-93 years). The incidence of ESI-related events was 0.46% per procedure, including 14 procedure-related complications, 56 drug-related systemic effects, and 174 events of uncertain cause. Of the 52,935 patients, 6 (0.011%) experienced major complications (two spine haematomas and four infections), 1 patient died, and 1 experienced neurological sequelae.
conclusionsAlthough major procedure-related complications and drug-related systemic effects of ESI requiring hospitalisation are very rare, infection and haematoma can occur, resulting in serious outcomes. Hence, ESI should be carefully considered in high-risk patients. KEY POINTS: • The incidence of ESI-related events requiring hospitalisation was 0.46%. • The incidence of procedure-related complications was 0.026%. • The incidence of drug-related systemic effects was 0.11%. • The incidence of major complication of ESI was 0.011%. • The major complications were spine infection, haematoma, and sepsis.
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