ArticleJournal of cancer research and clinical oncology2017
Dietary acrylamide exposure was associated with increased cancer mortality in Chinese elderly men and women: a 11-year prospective study of Mr. and Ms. OS Hong Kong.
Article in Journal of cancer research and clinical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 37 citations in OpenAlex.
- Association of acrylamide dietary intake with glycation and oxidative status biomarkers and intakes of advanced glycation end-products or alpha-dicarbonyls.Scientific reports · 2025Article
- Acrylamide Intake in Senior Center Canteens: A Total Exposure Assessment Applying the Duplicate Diet Approach.Foods (Basel, Switzerland) · 2025Article
- Global Research Hotspots and Progress on Acrylamide: Visualization Analysis.Environmental health insights · 2025Article
- Uncovering a New Concept of Foodnality in Diet Recommendations for Chinese Aging Populations Based on Systematic and Bibliometric Review.Foods (Basel, Switzerland) · 2024Review
- Dietary Exposure to Acrylamide Has Negative Effects on the Gastrointestinal Tract: A Review.Nutrients · 2024Review
- Dietary Acrylamide Exposure and Cancer Risk: A Systematic Approach to Human Epidemiological Studies.Foods (Basel, Switzerland) · 2023Review
- Determining the Levels of Acrylamide in Some Traditional Foods Unique to Turkey and Risk Assessment.Iranian journal of pharmaceutical research : IJPR · 2022Article
- A Review of Dietary Intake of Acrylamide in Humans.Toxics · 2021Review
- Article
- Bioremediation of a Common Product of Food Processing by a Human Gut Bacterium.Cell host & microbe · 2019Article
- Association of fried food consumption with all cause, cardiovascular, and cancer mortality: prospective cohort study.BMJ (Clinical research ed.) · 2019Article
- Dietary Acrylamide and the Risks of Developing Cancer: Facts to Ponder.Frontiers in nutrition · 2018Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
aimOur study aims to investigate the association between dietary acrylamide exposure and cancer mortality among Chinese elderly.
methodsA prospective cohort of 4000 elderly men and women aged 65 years and above (Mr. and Ms. OS Hong Kong study) was recruited from local communities from 2001 to 2003. Dietary exposure to acrylamide was evaluated at baseline based on a validated food frequency questionnaire and an acrylamide database from the 1st Hong Kong Total Diet Study. Data on mortality statistics through March 2014 were obtained from the Death Registry of the Department of Health of Hong Kong with a median follow-up of 11.1 years. Cox proportional hazards models were used to examine the association between the acrylamide exposure and cancer mortality. Sex hormones were assessed in men.
resultsDuring a median follow-up of 11.1 years (39,271 person-years), we ascertained 330 cancer deaths. Vegetables (43.7%) and cereals (28.9%) products were the major contributors to dietary acrylamide. Compared with the lowest quartile of acrylamide intake (<9.9 µg/day), the multivariable hazard ratios for the highest quartile (>17.1 µg/day) were 1.9 (95% CI 1.3-2.8; P
conclusionsThe longitudinal data provided evidence that dietary acrylamide, in amounts that Chinese elderly are typically exposed to, was associated with increased cancer mortality. Circulating free estradiol may mediate the association in men.
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