Evidence map›Paper›PMID 28726030›Full record

ReviewIrish journal of medical science2018

Intravascular large B-cell lymphoma presenting clinically as rapidly progressive dementia.

F M Brett, D Chen, T Loftus, Y Langan, S Looby, S Hutchinson

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Irish journal of medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Movement disorders in primary central nervous system lymphoma: two unreported cases and a review of literature.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Pooled it
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  5. Visual hallucinations as psychiatric onset of a primary central nervous system lymphoma: a case report and a brief review of literature on neoplasm-correlated neuropsychiatric disorders.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

F M BrettDepartment of Clinical Neurological Sciences, RCSI, Dublin 9, Ireland. francescabrett@rcsi.ie.ORCID http://orcid.org/0000-0002-7453-4027
D ChenDepartment of Clinical Neurological Sciences, RCSI, Dublin 9, Ireland.
T LoftusDepartment of Clinical Neurological Sciences, RCSI, Dublin 9, Ireland.
Y LanganDepartment of Neurology, St James Hospital, Dublin, Ireland.
S LoobyDepartment of Clinical Neurological Sciences, RCSI, Dublin 9, Ireland.
S HutchinsonDepartment of Neurology, St James Hospital, Dublin, Ireland.
Royal College of Surgeons in Ireland · IESt. James's Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients presenting with rapidly progressive dementia, prion disease may enter the differential diagnosis. The commonest malignancies masquerading as prion disease are primary CNS lymphoma and intravascular large B-cell lymphoma, both rare and difficult to diagnose without brain biopsy. CASE PRESENTATION: This 82-year-old lady with a past history of hypertension, presented with rapidly progressive cognitive impairment and ataxia. The possibility of sCJD was raised. Brain biopsy was carried out. Western blot for prion protein was negative. Brain biopsy showed intravascular large B-cell lymphoma. She died shortly afterwards.

conclusionThe clinical presentation of intravascular large B-cell lymphoma is diverse. Patients may present as in this case with dementia, seizures, and myoclonus leading to a clinical diagnosis of sCJD. The diagnosis here was made at biopsy but is made at autopsy in over 50% of cases.

Indexed as

Aged, 80 and overCreutzfeldt-Jakob SyndromeDementiaFemaleHumansIrelandLymphoma, Large B-Cell, DiffuseIVLBCL—intravascular large B-cell lymphomaPCNSL—primary CNS lymphomasCJD—sporadic CJD

Identifiers

PMID28726030
OpenAlexW2737407164

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.