ArticlePrevention science : the official journal of the Society for Prevention Research2019
Preventive Effect Heterogeneity: Causal Inference in Personalized Prevention.
Article in Prevention science : the official journal of the Society for Prevention Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Peer Network Counseling Effects on Substance Use: an Individual Participant Data Meta-Analysis Integrating Three Randomized Controlled Trials.Prevention science : the official journal of the Society for Prevention Research · 2023Pooled it
- Dynamic physiology-behavior association patterns in child welfare parents predict response to parenting intervention.Journal of consulting and clinical psychology · 2025Trial
- Heterogeneity in the Effects of Interventions to Prevent Depression in Couples Facing Job Loss: Studying Baseline Target Moderation of Impact.Prevention science : the official journal of the Society for Prevention Research · 2023Trial
- Emotion Regulation Difficulties in Military Fathers Magnify Their Benefit from a Parenting Program.Prevention science : the official journal of the Society for Prevention Research · 2023Trial
- Can We Uncouple Neighborhood Disadvantage and Delinquent Behaviors? An Experimental Test of Family Resilience Guided by the Social Disorganization Theory of Delinquent Behaviors.Family process · 2020Trial
- Testing Whether Protective Parenting is a Causal Mediator of Intervention Effects on Decreased Delinquency Using a Randomized Prevention Trial.Justice quarterly : JQ · 2024Article
- When Is It Time to Revise or Adapt Our Prevention Programs? Introduction to Special Issue on Using Baseline Target Moderation to Assess Variation in Prevention Impact.Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Secondary Analysis to Inform the Development of Adaptive Preventive Interventions.Clinical child and family psychology review · 2022Article
- How Early Stressful Life Experiences Combine With Adolescents' Conjoint Health Risk Trajectories to Influence Cardiometabolic Disease Risk in Young Adulthood.Journal of youth and adolescence · 2021Article
- Three Flavorings for a Soup to Cure what Ails Mental Health Services.Administration and policy in mental health · 2020Article
- Precision Strategies as a Timely and Unifying Framework for Ongoing Prevention Science Advances.Prevention science : the official journal of the Society for Prevention Research · 2019Article
- Moving Toward a Precision-Based, Personalized Framework for Prevention Science: Introduction to the Special Issue.Prevention science : the official journal of the Society for Prevention Research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
This paper employs a causal inference framework to explore two logically distinct forms of preventive effect heterogeneity relevant for studying variation in preventive effect as a basis for developing more personalized interventions. Following VanderWeele (2015), I begin with a discussion of causal interaction involving manipulable moderators that combine to yield more complex nonadditive effects. This is contrasted with effect heterogeneity, which involves variation in causal structure indexed by stable characteristics of populations or contexts. The paper then discusses one particularly promising approach, the baseline target moderated mediation (BTMM) design, which uses theoretically informed baseline target moderators to strengthen causal inference, suggesting methods for using BTMM designs to develop targeting strategies for personalized prevention. It presents examples of recent intervention trials that apply these different forms of moderation, and discusses causal inference and the problem of moderation confounding, reviewing methods for minimizing its impact, including recent advances in the use of propensity score matching.
Indexed as
Identifiers
28725991What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.