Evidence map›Paper›PMID 28725950›Full record

ArticleMedicine, health care, and philosophy2018

Genome editing and assisted reproduction: curing embryos, society or prospective parents?

Giulia Cavaliere

Abstract read
In one paragraph

Article in Medicine, health care, and philosophy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Gene Editing, Identity and Benefit.The Philosophical quarterly · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. The 'serious' factor in germline modification.Journal of medical ethics · 2019
    Article
  17. Article
  18. Regulating Genome Editing: For an Enlightened Democratic Governance.Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees · 2019
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Giulia CavaliereWellcome Trust PhD Student in Bioethics & Society, Department of Global Health & Social Medicine, King's College London, London, UK. giulia.cavaliere@kcl.ac.uk.ORCID http://orcid.org/0000-0001-8703-1499

Funding

Wellcome TrustWellcome Trust WT108623/Z/15/Z
6 · The paper itself

Abstract

This paper explores the ethics of introducing genome-editing technologies as a new reproductive option. In particular, it focuses on whether genome editing can be considered a morally valuable alternative to preimplantation genetic diagnosis (PGD). Two arguments against the use of genome editing in reproduction are analysed, namely safety concerns and germline modification. These arguments are then contrasted with arguments in favour of genome editing, in particular with the argument of the child's welfare and the argument of parental reproductive autonomy. In addition to these two arguments, genome editing could be considered as a worthy alternative to PGD as it may not be subjected to some of the moral critiques moved against this technology. Even if these arguments offer sound reasons in favour of introducing genome editing as a new reproductive option, I conclude that these benefits should be balanced against other considerations. More specifically, I maintain that concerns regarding the equality of access to assisted reproduction and the allocation of scarce resources should be addressed prior to the adoption of genome editing as a new reproductive option.

Indexed as

ChildChild WelfareFemaleGene EditingGenetic TestingGenetic TherapyHumansParentsPreimplantation DiagnosisReproductive TechniquesReproductive Techniques, AssistedAssisted reproductionGenetic kinshipGenome editingPGDSelectionTherapy

Identifiers

PMID28725950
PMCPMC5956052

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.