Evidence map›Paper›PMID 28725689›Full record

ArticleNPJ Parkinson's disease2015

Single injection of small-molecule amyloid accelerator results in cell death of nigral dopamine neurons in mice.

Maria Chermenina, Erik Chorell, Małgorzata Pokrzywa, Henrik Antti, Fredrik Almqvist, Ingrid Strömberg, Pernilla Wittung-Stafshede

Open access · goldAbstract read
In one paragraph

Article in NPJ Parkinson's disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Polyphenol-solubility alters amyloid fibril formation of α-synuclein.Protein science : a publication of the Protein Society · 2021
    Article
  6. Article
  7. Extracellular Vesicles in Neurodegenerative Diseases: A Double-Edged Sword.Tissue engineering and regenerative medicine · 2017
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maria ChermeninaDepartment of Integrative Medical Biology, Umeå University, Umeå, Sweden.
Erik ChorellDepartment of Chemistry, Umeå University, Umeå, Sweden.
Małgorzata PokrzywaAiroptic Sp. z o.o., ul. Rubież 46H, Poznań, Poland.
Henrik AnttiDepartment of Chemistry, Umeå University, Umeå, Sweden.
Fredrik AlmqvistDepartment of Chemistry, Umeå University, Umeå, Sweden.
Ingrid StrömbergDepartment of Integrative Medical Biology, Umeå University, Umeå, Sweden.
Pernilla Wittung-StafshedeDepartment of Chemistry, Umeå University, Umeå, Sweden.
Umeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The assembly process of α-synuclein toward amyloid fibers is linked to neurodegeneration in Parkinson's disease. In the present study, we capitalized on the

Identifiers

PMID28725689
PMCPMC5516562
OpenAlexW2278791776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.