Evidence map›Paper›PMID 28725670›Full record

ArticleData in brief2017

Fatty acid and lipidomic data in normal and tumor colon tissues of rats fed diets with and without fish oil.

Zora Djuric, Muhammad Nadeem Aslam, Becky R Simon, Ananda Sen, Yan Jiang, Jianwei Ren, Rena Chan, Tanu Soni, Thekkelnaycke M Rajendiran, William L Smith and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Zora DjuricDepartment of Family Medicine, University of Michigan, Ann Arbor, MI 48109, United States.
Muhammad Nadeem AslamDepartment of Pathology, University of Michigan, Ann Arbor, MI 48109, United States.
Becky R SimonDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, United States.
Ananda SenDepartment of Family Medicine, University of Michigan, Ann Arbor, MI 48109, United States.
Yan JiangDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, United States.
Jianwei RenDepartment of Family Medicine, University of Michigan, Ann Arbor, MI 48109, United States.
Rena ChanDepartment of Family Medicine, University of Michigan, Ann Arbor, MI 48109, United States.
Tanu SoniMichigan Metabolomics Resource Center, University of Michigan, Ann Arbor, MI 48109, United States.
Thekkelnaycke M RajendiranMichigan Metabolomics Resource Center, University of Michigan, Ann Arbor, MI 48109, United States.
William L SmithDepartment of Biochemistry, University of Michigan, Ann Arbor, MI 48109, United States.
Dean E BrennerDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, United States.
University of Michigan–Ann Arbor · US

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Gary D Luker · 1988 to 2026
$178.2M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Translational Research in GI CancerP50CA130810 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BRENNER, DEAN E. · 2010 to 2016
$11.8M
Statistics and Bioinformatics Core - WangU24DK097153 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BURANT, CHARLES F · 2012 to 2017
$10.1M
Training Program in Tumor MicroenvironmentT32CA009676 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Maria G Castro, Analisa Virginia DiFeo · 1992 to 2026
$7.3M
NCI NIH HHS P30 CA046592NCI NIH HHS P50 CA130810NCI NIH HHS T32 CA009676NIDDK NIH HHS P30 DK020572NIDDK NIH HHS U24 DK097153
6 · The paper itself

Abstract

Data is provided to show the detailed fatty acid and lipidomic composition of normal and tumor rat colon tissues. Rats were fed either a Western fat diet or a fish oil diet, and half the rats from each diet group were treated with chemical carcinogens that induce colon cancer (azoxymethane and dextran sodium sulfate). The data show total fatty acid profiles of sera and of all the colon tissues, namely normal tissue from control rats and both normal and tumor tissues from carcinogen-treated rats, as obtained by gas chromatography with mass spectral detection. Data from lipidomic analyses of a representative subset of the colon tissue samples is also shown in heat maps generated from hierarchical cluster analysis. These data display the utility lipidomic analyses to enhance the interpretation of dietary feeding studies aimed at cancer prevention and support the findings published in the companion paper (Effects of fish oil supplementation on prostaglandins in normal and tumor colon tissue: modulation by the lipogenic phenotype of colon tumors, Djuric et al., 2017 [1]).

Indexed as

Colon tumorigenesisDietFatty acidsFish oilsLipidomics

Identifiers

PMID28725670
PMCPMC5503825
OpenAlexW2658322821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.