Evidence map›Paper›PMID 28725471›Full record

ArticleNPJ systems biology and applications2016

Strategies for structuring interdisciplinary education in Systems Biology: an European perspective.

Marija Cvijovic, Thomas Höfer, Jure Aćimović, Lilia Alberghina, Eivind Almaas, Daniela Besozzi, Anders Blomberg, Till Bretschneider, Marta Cascante, Olivier Collin and 23 more

Open access · goldAbstract read
In one paragraph

Article in NPJ systems biology and applications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 20 institutions in 14 countries.

Marija CvijovicDepartment of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, Gothenburg, Sweden.
Thomas HöferDivision of Theoretical Systems Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Jure AćimovićCentre for Functional Genomics and Bio-Chips, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Lilia AlberghinaUniversity of Milano-Bicocca, Department of Biotechnology and Biosciences, Milano, Italy.ORCID 0000-0003-1694-931X
Eivind AlmaasDepartment of Biotechnology, NTNU - Norwegian University of Science and Technology, Trondheim, Norway.
Daniela BesozziDepartment of Informatics, Systems and Communication, University of Milano-Bicocca and SYSBIO Centre of Systems Biology, Milano, Italy.
Anders BlombergDepartment of Marine Sciences, University of Gothenburg, Gothenburg, Sweden.
Till BretschneiderWarwick Systems Biology Centre, University of Warwick, Warwick, UK.ORCID 0000-0002-5317-603X
Marta CascanteDepartment of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, Barcelona, Spain.
Olivier CollinCNRS, Paris, France.
Pedro de AtauriDepartment of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, Barcelona, Spain.
Cornelia DepnerDivision of Theoretical Systems Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Robert DickinsonImperial College London, London, UK.
Maciej DobrzynskiUniversity College Dublin, Dublin, Ireland.
Christian FleckLaboratory for Systems and Synthetic Biology, Wageningen UR, Wageningen, Netherlands.
Jordi Garcia-OjalvoUniversitat Pompeu Fabra, Department of Experimental and Health Sciences, Barcelona, Spain.ORCID 0000-0002-3716-7520
Didier GonzeUnité de Chronobiologie Théorique, Faculté des Sciences, CP 231 and Interuniversity Institute of Bioinformatics in Brussels (IB)2, Université Libre de Bruxelles, Brussels, Belgium.
Jens HahnTheoretical Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0003-2200-6553
Heide Marie HessSystemsX.ch, Zurich, Switzerland.
Susanne HollmannLifeGlimmer GmbH, Berlin, Germany.
Marcus KrantzTheoretical Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.
Ursula KummerUniversity of Heidelberg, Heidelberg, Germany.
Torbjörn LundhDepartment of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, Gothenburg, Sweden.
Gifta MartialBioQuant Center, University of Heidelberg, Heidelberg, Germany.
Vítor Martins Dos SantosWageningen UR, Netherlands.
Angela Mauer-OberthürBioQuant Center, University of Heidelberg, Heidelberg, Germany.
Babette RegiererLifeGlimmer GmbH, Berlin, Germany.ORCID 0000-0002-5263-4553
Barbara SkeneImperial College London, London, UK.
Egils StalidzansInstitute of Microbiology and Biotechnology, University of Latvia, Riga, Latvia.
Jörg StellingETH Zurich, Zurich, Switzerland.
Bas TeusinkVrije Universiteit Amsterdam, Amsterdam, Netherlands.
Christopher T WorkmanTechnical University of Denmark, Copenhagen, Denmark.
Stefan HohmannDepartment of Biology and Bioengineering, Chalmers University of Technology, Göteborg, Sweden.
Chalmers University of Technology · SEHeidelberg University · DEGerman Cancer Research Center · DEHumboldt-Universität zu Berlin · DEImperial College London · GBLifeGlimmer (Germany) · DEUniversitat de Barcelona · ESUniversity of Milano-Bicocca · ITWageningen University & Research · NLCentre National de la Recherche Scientifique · FRETH Zurich · CHNorwegian University of Science and Technology · NOSystemsX.ch · CHTechnical University of Denmark · DKUniversitat Pompeu Fabra · ESUniversité Libre de Bruxelles · BEUniversity College Dublin · IEUniversity of Gothenburg · SEUniversity of Latvia · LVUniversity of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systems Biology is an approach to biology and medicine that has the potential to lead to a better understanding of how biological properties emerge from the interaction of genes, proteins, molecules, cells and organisms. The approach aims at elucidating how these interactions govern biological function by employing experimental data, mathematical models and computational simulations. As Systems Biology is inherently multidisciplinary, education within this field meets numerous hurdles including departmental barriers, availability of all required expertise locally, appropriate teaching material and example curricula. As university education at the Bachelor's level is traditionally built upon disciplinary degrees, we believe that the most effective way to implement education in Systems Biology would be at the Master's level, as it offers a more flexible framework. Our team of experts and active performers of Systems Biology education suggest here (i) a definition of the skills that students should acquire within a Master's programme in Systems Biology, (ii) a possible basic educational curriculum with flexibility to adjust to different application areas and local research strengths, (iii) a description of possible career paths for students who undergo such an education, (iv) conditions that should improve the recruitment of students to such programmes and (v) mechanisms for collaboration and excellence spreading among education professionals. With the growing interest of industry in applying Systems Biology approaches in their fields, a concerted action between academia and industry is needed to build this expertise. Here we present a reflection of the European situation and expertise, where most of the challenges we discuss are universal, anticipating that our suggestions will be useful internationally. We believe that one of the overriding goals of any Systems Biology education should be a student's ability to phrase and communicate research questions in such a manner that they can be solved by the integration of experiments and modelling, as well as to communicate and collaborate productively across different experimental and theoretical disciplines in research and development.

Identifiers

PMID28725471
PMCPMC5516850
OpenAlexW2404535238

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.