ReviewClinical and translational allergy2017
Diagnosing allergic sensitizations in the third millennium: why clinicians should know allergen molecule structures.
Review in Clinical and translational allergy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 46 citations in OpenAlex.
- Bioassays in Allergy: Technical Characteristics, Limitations, and Pathways to Clinical Implementation-An EAACI Position Paper.Clinical and translational allergy · 2026Review
- Evidence-Based Clinical Recommendations for the Appropriate Use of Diagnostic Tests in Pediatric Allergology: Focus on Asthma, Rhinoconjunctivitis, and Keratoconjunctivitis Vernal.Journal of clinical medicine · 2026Review
- Selected Technical Aspects of Molecular Allergy Diagnostics.Current issues in molecular biology · 2023Review
- Detection of Allergenic Proteins in Foodstuffs: Advantages of the Innovative Multiplex Allergen Microarray-Based Immunoassay Compared to Conventional Methods.Foods (Basel, Switzerland) · 2022Review
- Crosstalk Between the Immune System and Plant-Derived Nanovesicles: A Study of Allergen Transporting.Frontiers in bioengineering and biotechnology · 2021Article
- VALIDA project: Validation of allergyAdvances in laboratory medicine · 2020Review
- Allergic rhinoconjunctivitis: pathophysiological mechanism and new therapeutic approach.Acta bio-medica : Atenei Parmensis · 2020Article
- New Perspectives in Food Allergy.International journal of molecular sciences · 2020Review
- Molecular approach to a patient's tailored diagnosis of the oral allergy syndrome.Clinical and translational allergy · 2020Review
- Use of Humanized Fluorescent Reporter Cell Line RBL NFAT-DsRed for the Detection of Allergen-Specific IgE in Patient Sera Using Allergen Microarrays.Methods in molecular biology (Clifton, N.J.) · 2020Article
- Structural Analysis of Recent Allergen-Antibody Complexes and Future Directions.Current allergy and asthma reports · 2019Review
- Microarray Immunodiagnostics for Aeroallergens.Current allergy and asthma reports · 2019Review
- Plant-Made Bet v 1 for Molecular Diagnosis.Frontiers in plant science · 2019Article
- An evaluation of veterinary allergen extract content and resultant canine intradermal threshold concentrations.Veterinary dermatology · 2018Article
- Precision medicine allergy immunoassay methods for assessing immunoglobulin E sensitization to aeroallergen molecules.World journal of methodology · 2018Article
- The potential of component-resolved diagnosis in laboratory diagnostics of allergy.Biochemia medica · 2018Review
- Highlights and recent developments in airway diseases in EAACI journals (2017).Clinical and translational allergy · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diagnostic tests to detect allergic sensitization were introduced at the end of the nineteenth century but only in the late 1990s did the advent of molecular allergology revolutionize the approach to the allergic patient. Personalized Medicine, a medical procedure that separates patients into different groups with different medical decisions, practices and interventions has sanctioned this change. In fact, in the last few years molecular allergology and the observation that not every patient has the same allergic profile, even when allergic to the same allergenic source, has originated the concept "one size does not fit all". This new approach requires the identification of still unknown allergens, but also the more detailed investigation of those already known. In depth studies of the structure-function relationships in allergenic molecules can reveal the structural determinants involved in the IgE-binding. Then, the knowledge of the epitope profile of each allergen and of the environmental/experimental conditions affecting the exposure of IgE-binding epitopes can provide important contributions to the understanding of cross-reaction processes and to the improvement of diagnosis, immunotherapy and the overall patient treatment. The evolution of diagnostic systems cannot ignore these new needs in this field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.