Evidence map›Paper›PMID 28725325›Full record

ArticleCardiology research2017

Left Atrial Appendage Volume and Plasma Docosahexaenoic Acid Levels Are Associated With Atrial Fibrillation Recurrence After Catheter Ablation.

Tomoyuki Shiozawa, Kazunori Shimada, Gaku Sekita, Hidemori Hayashi, Haruna Tabuchi, Seiji Miura, Shinichiro Fujimoto, Tomoyasu Kadoguchi, Shohei Ouchi, Tatsuro Aikawa and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Cardiology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Left atrial appendage morphofunctional indices could be predictive of arrhythmia recurrence post-atrial fibrillation ablation: a meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Tomoyuki ShiozawaDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kazunori ShimadaDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Gaku SekitaDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hidemori HayashiDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Haruna TabuchiDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Seiji MiuraDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Shinichiro FujimotoDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tomoyasu KadoguchiDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Shohei OuchiDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tatsuro AikawaDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hamad Al ShahiDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Shuhei TakahashiDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tetsuro MiyazakiDepartment of Cardiology, Juntendo University Urayasu Hospital, Chiba, Japan.
Masataka SumiyoshiDepartment of Cardiology, Juntendo University Nerima Hospital, Tokyo, Japan.
Yuji NakazatoDepartment of Cardiology, Juntendo University Urayasu Hospital, Chiba, Japan.
Hiroyuki DaidaDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Juntendo University · JPJuntendo University Urayasu Hospital · JPJuntendo University Nerima Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRisk factors for atrial fibrillation (AF) recurrence in patients who have undergone AF catheter ablation have not been fully clarified. The objective of this study was to assess whether the left atrium (LA) and LA appendage (LAA) volumes, and cardio-metabolic markers such as polyunsaturated fatty acids (PUFAs) levels were associated with AF recurrence.

methodsSeventy-seven consecutive patients with AF (mean age, 59 ± 8 years; male, 81%; paroxysmal AF, 64%) undergoing catheter ablation were enrolled. Using contrast-enhanced cardiac multi-detector computed tomography (MDCT) scan, the LA and LAA volume and orifice area were assessed. Radiofrequency ablation was performed by an irrigation catheter, initially targeting the pulmonary veins with a wide area circumferential ablation.

resultsPatients with AF recurrence (36%) exhibited both larger LAA volumes and an LAA orifice area than those without AF recurrence, whereas the LA diameter and LA volumes were not significantly different. Notably, AF recurrence occurred in all patients with a large LAA (≥ 25 mL), and the LAA volume was significantly and negatively associated with docosahexaenoic acid (DHA) levels (β = -0.33, P = 0.003). A multiple regression analysis revealed that the log N-terminal proB-type natriuretic peptide and plasma DHA levels were independent factors for the LAA volume when adjusted for age, AF detected age, left ventricular (LV) ejection fraction, end-systolic LV diameter.

conclusionsThese results suggest that the association between LAA volume and low plasma DHA levels may be an important factor for post-ablation AF recurrence.

Indexed as

Atrial fibrillationCatheter ablationDocosahexaenoic acidLeft atrial appendage

Identifiers

PMID28725325
PMCPMC5505292
OpenAlexW2733734661

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.