Evidence map›Paper›PMID 28725324›Full record

ReviewCardiology research2017

Cardiorenal Syndrome: Role of Arginine Vasopressin and Vaptans in Heart Failure.

Poornima Vinod, Vinod Krishnappa, Abigail M Chauvin, Anshika Khare, Rupesh Raina

Open access · diamondAbstract readReview
In one paragraph

Review in Cardiology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Right Heart Function in Cardiorenal Syndrome.Current heart failure reports · 2022
    Pooled it
  3. Article
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  8. Apela inhibits systemic and renal inflammatory reactions in mice with type I cardiorenal syndrome.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
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  17. Article
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  19. Article
  20. Hyponatremia: A role for vasopressin receptor antagonists?Journal of anaesthesiology, clinical pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Poornima VinodDepartment of Internal Medicine, Cleveland Clinic Akron General, Akron, OH, USA.
Vinod KrishnappaCleveland Clinic Akron General/Akron Nephrology Associates, Akron, OH, USA.
Abigail M ChauvinNortheast Ohio Medical University, Rootstown, OH, USA.
Anshika KhareNortheast Ohio Medical University, Rootstown, OH, USA.
Rupesh RainaDepartment of Nephrology, Cleveland Clinic Akron General, Akron, OH, USA.
Cleveland Clinic · USNortheast Ohio Medical University · USAkron General Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart and kidney failure continued to be of increasing prevalence in today's society, and their comorbidity has synergistic effect on the morbidity and mortality of patients. Cardiorenal syndrome (CRS) is a complex disease with multifactorial pathophysiology. Better understanding of this pathophysiological network is crucial for the successful intervention to prevent advancement of the disease process. One of the major factors in this process is neurohormonal activation, predominantly involving renin-angiotensin-aldosterone system (RAAS) and arginine vasopressin (AVP). Heart failure causes reduced cardiac output/cardiac index (CO/CI) and fall in renal perfusion pressures resulting in activation of baroreceptors and RAAS, respectively. Activated baroreceptors and RAAS stimulate the release of AVP (non-osmotic pathway), which acts on V

Indexed as

Arginine vasopressinCardiorenal syndromeConivaptanHeart failureTolvaptanVaptansVasopressin receptor antagonists

Identifiers

PMID28725324
PMCPMC5505291
OpenAlexW2726497265

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.