ArticleThe EPMA journal2017
Relationship between normal tension glaucoma and Flammer syndrome.
Article in The EPMA journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Diet, Oxidative Stress, and Blood Serum Nutrients in Various Types of Glaucoma: A Systematic Review.Nutrients · 2022Pooled it
- Ocular Blood Flow in Eyes with Myopia and Glaucoma: From Pathophysiology to Clinical Implications.Journal of clinical medicine · 2026Review
- Cold Extremities and Underweight as a Combined Risk Profile for Open-Angle Glaucoma: A Population-Based Cross-Sectional Study in Korea.Medicina (Kaunas, Lithuania) · 2026Article
- Primary Vascular Dysregulation in Normal-Tension Glaucoma: Pathophysiology and Management.Cureus · 2026Review
- Disease Diagnosis Using Retinal Vasculature: Insights from Flammer Syndrome and AI.Brain sciences · 2025Review
- Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition.Translational vision science & technology · 2025Article
- [Glaucoma Patient with Suspected Flammer Syndrome: Diagnostic Procedures and Therapeutic Implications].Klinische Monatsblatter fur Augenheilkunde · 2024Review
- Stress, Allostatic Load, and Neuroinflammation: Implications for Racial and Socioeconomic Health Disparities in Glaucoma.International journal of molecular sciences · 2024Review
- Retinal microvasculature features in patients with migraine: a systematic review and meta-analysis.Frontiers in neurology · 2023Review
- Treatment of Glaucoma Patients with Flammer Syndrome.Journal of clinical medicine · 2021Review
- Neuroprotection in Glaucoma: NADCells · 2021Review
- [Vasculat treatment concepts in glaucoma patients].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021Review
- Health screening program revealed risk factors associated with development and progression of papillomacular bundle defect.The EPMA journal · 2021Article
- Oxidative Stress and the Role of NADPH Oxidase in Glaucoma.Antioxidants (Basel, Switzerland) · 2021Review
- Examining risk factors related to digital learning and social isolation: Youth visual acuity in COVID-19 pandemic.Journal of global health · 2021Observational
- Contributions to Progress in Ophthalmology from Switzerland: From the 16th to the 21st Century.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2021Review
- Systemic Vascular Dysregulation May Be Associated With Lower Peripapillary Vessel Density in Non-glaucomatous Healthy Eyes: A Prospective Cross-Sectional Study.Frontiers in medicine · 2021Article
- Personality and stress influence vision restoration and recovery in glaucoma and optic neuropathy following alternating current stimulation: implications for personalized neuromodulation and rehabilitation.The EPMA journal · 2020Article
- Flammer syndrome in multiple sclerosis: diagnostics, prediction, and personalization of treatments.The EPMA journal · 2019Article
- Cholinergic nervous system and glaucoma: From basic science to clinical applications.Progress in retinal and eye research · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBesides intraocular pressure, vascular factors play a role in the pathogenesis of glaucomatous optic neuropathy. One of these potential vascular factors is Flammer syndrome. The purpose of the present study was to determine in a Korean population whether signs and symptoms of Flammer syndrome occur more often in normal tension glaucoma patients than in control subjects.
methodsTwo hundred forty-six normal tension glaucoma patients and 1116 control subjects responded to a multiple-choice questionnaire asking about 15 signs and symptoms of Flammer syndrome.
resultsSeven of the 15 signs and symptoms of Flammer syndrome (increased drug sensitivity, good smell perception, reversible skin blotches, tinnitus, long sleep onset time, tendency to perfectionism, and cold hands/feet) were significantly more often positive in normal tension glaucoma patients than in controls. Six additional signs and symptoms (migraines, low blood pressure, headaches, dizziness, increased pain sensation, and feeling cold) also occurred more often, but did not reach statistical significance. Only two items (low body weight and reduced feeling of thirst) were more frequently (not significant) positive in the controls.
conclusionThere is an association between normal tension glaucoma and Flammer syndrome. If future studies confirm this relationship, treatment of Flammer syndrome may help to prevent normal tension glaucoma or to slow down its progression.
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