ArticleNew journal of physics2015
Continuum theory of gene expression waves during vertebrate segmentation.
Article in New journal of physics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Ripply suppresses Tbx6 to induce dynamic-to-static conversion in somite segmentation.Nature communications · 2023Article
- Towards a physical understanding of developmental patterning.Nature reviews. Genetics · 2021Review
- Time and space in segmentation.Interface focus · 2021Article
- From local resynchronization to global pattern recovery in the zebrafish segmentation clock.eLife · 2021Article
- Article
- Constraints on somite formation in developing embryos.Journal of the Royal Society, Interface · 2019Article
- The proneural wave in theeLife · 2019Article
- Size-reduced embryos reveal a gradient scaling-based mechanism for zebrafish somite formation.Development (Cambridge, England) · 2018Article
- A framework for quantification and physical modeling of cell mixing applied to oscillator synchronization in vertebrate somitogenesis.Biology open · 2017Article
- Sequential pattern formation governed by signaling gradients.Physical biology · 2016Article
- Faster embryonic segmentation through elevated Delta-Notch signalling.Nature communications · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The segmentation of the vertebrate body plan during embryonic development is a rhythmic and sequential process governed by genetic oscillations. These genetic oscillations give rise to traveling waves of gene expression in the segmenting tissue. Here we present a minimal continuum theory of vertebrate segmentation that captures the key principles governing the dynamic patterns of gene expression including the effects of shortening of the oscillating tissue. We show that our theory can quantitatively account for the key features of segmentation observed in zebrafish, in particular the shape of the wave patterns, the period of segmentation and the segment length as a function of time.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.