ArticleScientific reports2017
CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Dynamic regulation of CD300b and CD300f on myeloid cells in oral immunotherapy.The journal of allergy and clinical immunology. Global · 2026Article
- A Short-Term High-Sugar Diet Induces Glucose Intolerance, Visceral Adipose Tissue Inflammation, and Exacerbates Experimental Allergic Asthma.Nutrients · 2026Article
- Beyond BMI: visceral adiposity assessed by the lipid accumulation product index shows independent associations with IL-5 and TNF-β in older adults.Aging clinical and experimental research · 2026Article
- Role of the Th2-like Immune Response in Obesity: IL-4 as a Metabolic Regulator and IL-13 as an Effector of Muscle Energy Metabolism.Biomedicines · 2025Review
- Article
- Eosinophils in obesity and obesity-associated disorders.Discovery immunology · 2023Review
- Immune Cells in Thermogenic Adipose Depots: The Essential but Complex Relationship.Frontiers in endocrinology · 2022Review
- Differential regulation of Type 1 and Type 2 mouse eosinophil activation by apoptotic cells.Frontiers in immunology · 2022Article
- Rebamipide treatment ameliorates obesity phenotype by regulation of immune cells and adipocytes.PloS one · 2022Article
- Bidirectional crosstalk between eosinophils and esophageal epithelial cells regulates inflammatory and remodeling processes.Mucosal immunology · 2021Article
- Eosinophil Knockout Humans: Uncovering the Role of Eosinophils Through Eosinophil-Directed Biological Therapies.Annual review of immunology · 2021Article
- The Expression and Function of CD300 Molecules in the Main Players of Allergic Responses: Mast Cells, Basophils and Eosinophils.International journal of molecular sciences · 2020Review
- Contributions of Eosinophils to Human Health and Disease.Annual review of pathology · 2020Review
- Contributions of innate type 2 inflammation to adipose function.Journal of lipid research · 2019Review
- The Role of NADPH Oxidases in the Etiology of Obesity and Metabolic Syndrome: Contribution of Individual Isoforms and Cell Biology.Antioxidants & redox signaling · 2019Review
- Eosinophils support adipocyte maturation and promote glucose tolerance in obesity.Scientific reports · 2018Article
- Elevating adipose eosinophils in obese mice to physiologically normal levels does not rescue metabolic impairments.Molecular metabolism · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
Eosinophils and their associated cytokines IL-4 and IL-5 are emerging as central orchestrators of the immune-metabolic axis. Herein, we demonstrate that cross-talk between the Ig-superfamily receptor CD300f and IL-5 is a key checkpoint that modifies the ability of eosinophils to regulate metabolic outcomes. Generation of Il5
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.