Evidence map›Paper›PMID 28724951›Full record

ArticleScientific reports2017

N-terminal pro-brain natriuretic peptide and associated factors in the general working population: a baseline survey of the Uranosaki cohort study.

Atsushi Tanaka, Hisako Yoshida, Atsushi Kawaguchi, Jun-Ichi Oyama, Norihiko Kotooka, Shigeru Toyoda, Teruo Inoue, Masafumi Natsuaki, Koichi Node

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Atsushi TanakaDepartment of Cardiovascular Medicine, Saga University, Saga, Japan. tanakaa2@cc.saga-u.ac.jp.
Hisako YoshidaClinical Research Center, Saga University, Saga, Japan.
Atsushi KawaguchiClinical Research Center, Saga University, Saga, Japan.
Jun-Ichi OyamaDepartment of Cardiovascular Medicine, Saga University, Saga, Japan.
Norihiko KotookaDepartment of Cardiovascular Medicine, Saga University, Saga, Japan.ORCID 0000-0002-7375-4984
Shigeru ToyodaDepartment of Cardiovascular Medicine, Dokkyo Medical University, Mibu, Japan.
Teruo InoueDepartment of Cardiovascular Medicine, Dokkyo Medical University, Mibu, Japan.
Masafumi NatsuakiDepartment of Internal Medicine, Imari Matsuura Hospital, Imari, Japan.
Koichi NodeDepartment of Cardiovascular Medicine, Saga University, Saga, Japan. node@cc.saga-u.ac.jp.ORCID 0000-0002-2534-0939
Saga University · JPDokkyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few data on clinical characteristics associated with N-terminal pro-brain natriuretic peptide (NT-proBNP) or the clinical value of measuring NT-proBNP in the working population are available. The aim of the present study was to investigate the levels of NT-proBNP and their association with clinical variables in the Japanese general working population by using baseline data from the Uranosaki cohort study. In the study, the plasma concentration of NT-proBNP and some biomarkers were measured in addition to the standard health checkups at the workplace. Questionnaires regarding health-related quality of life (HR-QOL) were also completed. A total of 2140 participants were enrolled in the study. Plasma levels of NT-proBNP were positively associated with age, female sex, systolic blood pressure, pulse pressure, prevalent hypertension, smoking habit, high-density lipoprotein cholesterol (HDL-C), and prevalent proteinuria, and negatively associated with body mass index, lipid profiles except HDL-C, uric acid, renal function, and hemoglobin. Both the plasma concentration of high-molecular weight adiponectin and that of high-sensitivity troponin T were positively and independently associated with NT-proBNP. In addition, the HR-QOL score regarding sleep disorder was independently associated with NT-proBNP. Thus, we have obtained evidence that the plasma NT-proBNP is affected by several clinical variables in the general working population.

Indexed as

Surveys and QuestionnairesAdultAgedCohort StudiesFemaleHumansMaleMiddle AgedMultivariate AnalysisNatriuretic Peptide, BrainPeptide FragmentsQuality of LifeRegression AnalysisRisk FactorsWorkNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)

Identifiers

PMID28724951
PMCPMC5517578
OpenAlexW2735834300

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.