Evidence map›Paper›PMID 28724757›Full record

ArticleJournal of cell science2017

Molecular anatomy of the early events in STIM1 activation - oligomerization or conformational change?

Marek K Korzeniowski, Eva Wisniewski, Barbara Baird, David A Holowka, Tamas Balla

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Multiple weak brakes act in concert to control STIM1 and store-operated calcium entry.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. Article
  5. Role of Store-Operated CaBiomolecules · 2021
    Review
  6. STIM Proteins: An Ever-Expanding Family.International journal of molecular sciences · 2020
    Review
  7. Mechanism of STIM activation.Current opinion in physiology · 2020
    Article
  8. STIM calcium sensing and conformational change.The Journal of physiology · 2020
    Review
  9. Store-Operated Calcium Channels: From Function to Structure and Back Again.Cold Spring Harbor perspectives in biology · 2020
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marek K KorzeniowskiSection on Molecular Signal Transduction, Program for Developmental Neuroscience, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD 20892, USA.
Eva WisniewskiSection on Molecular Signal Transduction, Program for Developmental Neuroscience, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD 20892, USA.
Barbara BairdDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
David A HolowkaDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
Tamas BallaSection on Molecular Signal Transduction, Program for Developmental Neuroscience, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD 20892, USA ballat@mail.nih.gov.ORCID http://orcid.org/0000-0002-9077-3335
National Institutes of Health · USCornell University · US

Funding

Phosphoinositide-calcium Signaling In Cell RegulationZIAHD000196 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BALLA, TAMAS · 2009 to 2025
$26.3M
INTERACTIVE STRUCTURES AND DYNAMICS OF ANTIGEN RECEPTORSR01AI022449 · NIAID · CORNELL UNIVERSITY ITHACA · PI HOLOWKA, DAVID A · 1985 to 2014
$3.6M
High Resolution Characterization of Receptor Signaling and RegulationR01GM117552 · NIGMS · CORNELL UNIVERSITY · PI BAIRD, BARBARA A, HOLOWKA, DAVID A · 2016 to 2023
$3.2M
NIAID NIH HHS R01 AI022449NIGMS NIH HHS R01 GM117552
6 · The paper itself

Abstract

Decreased luminal endoplasmic reticulum (ER) Ca

Indexed as

Protein MultimerizationAnimalsCell SurvivalChlorocebus aethiopsCOS CellsImaging, Three-DimensionalMutationProtein ConformationProtein DomainsProtein StabilityStromal Interaction Molecule 1Stromal Interaction Molecule 1Ca2+Ca2+ entryEndoplasmic reticulumORAI1STIM1

Identifiers

PMID28724757
PMCPMC5612226
OpenAlexW2737866930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.