Evidence map›Paper›PMID 28724723›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Nucleoredoxin guards against oxidative stress by protecting antioxidant enzymes.

Sophie Kneeshaw, Rumana Keyani, Valérie Delorme-Hinoux, Lisa Imrie, Gary J Loake, Thierry Le Bihan, Jean-Philippe Reichheld, Steven H Spoel

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 129 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. The Wheat NucleoredoxinPlants (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. The ascorbate-glutathione cycle coming of age.Journal of experimental botany · 2024
    Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Sophie KneeshawSchool of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom.
Rumana KeyaniSchool of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom.
Valérie Delorme-HinouxUniversité Perpignan Via Domitia, CNRS, Laboratoire Génome et Développement des Plantes, F-66860, Perpignan, France.
Lisa ImrieSchool of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom.
Gary J LoakeSchool of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom.
Thierry Le BihanSchool of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom.ORCID http://orcid.org/0000-0003-0498-8063
Jean-Philippe ReichheldUniversité Perpignan Via Domitia, CNRS, Laboratoire Génome et Développement des Plantes, F-66860, Perpignan, France.
Steven H SpoelSchool of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom; steven.spoel@ed.ac.uk.ORCID http://orcid.org/0000-0003-4340-7591
University of Edinburgh · GBCentre National de la Recherche Scientifique · FR

Funding

Biotechnology and Biological Sciences Research Council BB/D011809/1Biotechnology and Biological Sciences Research Council BB/H000984/1
6 · The paper itself

Abstract

Cellular accumulation of reactive oxygen species (ROS) is associated with a wide range of developmental and stress responses. Although cells have evolved to use ROS as signaling molecules, their chemically reactive nature also poses a threat. Antioxidant systems are required to detoxify ROS and prevent cellular damage, but little is known about how these systems manage to function in hostile, ROS-rich environments. Here we show that during oxidative stress in plant cells, the pathogen-inducible oxidoreductase Nucleoredoxin 1 (NRX1) targets enzymes of major hydrogen peroxide (H

Indexed as

catalaseNucleoredoxinoxidative stressreactive oxygen speciesThioredoxin

Identifiers

PMID28724723
PMCPMC5547615
OpenAlexW2737873067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.