Evidence map›Paper›PMID 28724649›Full record

ArticleJournal of the American Heart Association2017

Significant Associations of Neurological Complications of Herpes Zoster With Stroke in Rheumatoid Arthritis Patients.

Tsai-Ling Liao, Ching-Heng Lin, Hsin-Hua Chen, Yi-Ming Chen, Che-Chen Lin, Der-Yuan Chen

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tsai-Ling LiaoDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Ching-Heng LinDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Hsin-Hua ChenDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Yi-Ming ChenDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Che-Chen LinDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Der-Yuan ChenDepartment of Internal Medicine and Medical Education, Taichung Veterans General Hospital, Taichung, Taiwan dychen@vghtc.gov.tw.
National Taipei University of Nursing and Health Science · TWNational Yang Ming Chiao Tung University · TWTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccumulating evidence suggests an increased risk of stroke after herpes zoster (HZ). This risk is elevated in immunocompromised patients. The incidence of HZ in Asia is higher than in Western countries. However, the epidemiology of HZ and HZ-related stroke among rheumatoid arthritis (RA) patients in Asia remains unclear. METHODS AND

resultsWe conducted a retrospective cohort study using a population-based database to investigate the epidemiology of HZ in RA patients in Taiwan during the period of 2000-2011. A total of 27 609 newly diagnosed and eligible RA cases were identified, and 110 436 non-RA cases were matched for age and sex at a ratio of 4:1. HZ risk increased by 2.53-fold (

conclusionsThe risk of HZ and HZ-related stroke has increased in RA patients. Monitoring the occurrence of HZ in RA patients and preventing HZ-related stroke or mortality during a specific immunosuppressive therapy are important.

Indexed as

AdultAgedAntirheumatic AgentsArthritis, RheumatoidChi-Square DistributionDatabases, FactualFemaleHerpesvirus 3, HumanHerpes ZosterHost-Pathogen InteractionsHumansImmunocompromised HostImmunosuppressive AgentsLogistic ModelsMaleMiddle AgedAntirheumatic AgentsImmunosuppressive Agentsherpes zosterimmunosuppressive therapyinfectious diseasenervous systemneurological complicationsrheumatoid arthritisstroke

Identifiers

PMID28724649
PMCPMC5586320
OpenAlexW2737243403

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.