Evidence map›Paper›PMID 28724635›Full record

ArticleThe Journal of biological chemistry2017

Heterodimers of the transcriptional factors NFATc3 and FosB mediate tissue factor expression for 15(

Sivareddy Kotla, Nikhlesh K Singh, Daniel Kirchhofer, Gadiparthi N Rao

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Identification of the function ofTranslational cancer research · 2023
    Article
  3. The role of monocytes in thrombotic diseases: a review.Frontiers in cardiovascular medicine · 2023
    Review
  4. Dynamic changes in β-cell [CaMolecular metabolism · 2022
    Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sivareddy KotlaFrom the Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163 and.
Nikhlesh K SinghFrom the Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163 and.
Daniel KirchhoferDepartment of Early Discovery Biochemistry, Genentech Inc., South San Francisco, California 94080.
Gadiparthi N RaoFrom the Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163 and.
University of Tennessee Health Science Center · US

Funding

PLA2, EICOSANOIDS AND VASCULAR REMODELINGR01HL064165 · NHLBI · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI RAO, GADIPARTHI N · 2000 to 2016
$5.4M
GPCR Signaling & Vascular Wall RemodelingR01HL103575 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI RAO, GADIPARTHI N · 2011 to 2019
$4.1M
NHLBI NIH HHS R01 HL064165NHLBI NIH HHS R01 HL103575
6 · The paper itself

Abstract

Tissue factor (TF) is expressed in vascular and nonvascular tissues and functions in several pathways, including embryonic development, inflammation, and cell migration. Many risk factors for atherosclerosis, including hypertension, diabetes, obesity, and smoking, increase TF expression. To better understand the TF-related mechanisms in atherosclerosis, here we investigated the role of 12/15-lipoxygenase (12/15-LOX) in TF expression. 15(

Indexed as

AnimalsArachidonate 12-LipoxygenaseArachidonate 15-LipoxygenaseCell MovementCells, CulturedHumansHydroxyeicosatetraenoic AcidsMacrophagesMiceMice, Inbred C57BLMice, KnockoutMonocytesNFATC Transcription FactorsProto-Oncogene MasProto-Oncogene Proteins c-fosReactive Oxygen Species12-15-lipoxygenaseArachidonate 12-LipoxygenaseArachidonate 15-LipoxygenaseFOSB protein, humanHydroxyeicosatetraenoic AcidsMAS1 protein, humanNFATC3 protein, humanNFATC Transcription FactorsProto-Oncogene MasProto-Oncogene Proteins c-fosReactive Oxygen SpeciesThromboplastingene expressionmigrationmonocytesignal transductiontrafficking

Identifiers

PMID28724635
PMCPMC5592668
OpenAlexW2739181200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.