Evidence map›Paper›PMID 28724525›Full record

ArticleThe Journal of cell biology2017

TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import.

Wei Wang, Zhi-Jie Xia, Jean-Claude Farré, Suresh Subramani

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Mulibrey Nanism: Clinical Spectrum and Molecular Pathogenesis.International journal of molecular sciences · 2026
    Review
  3. ALKBH5/IGF2BP1-mediated mCell biology and toxicology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Mammalian pexophagy at a glance.Journal of cell science · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wei WangSection of Molecular Biology, Division of Biological Sciences, University of California, San Diego, La Jolla, CA.
Zhi-Jie XiaSection of Molecular Biology, Division of Biological Sciences, University of California, San Diego, La Jolla, CA.ORCID 0000-0003-3018-1925
Jean-Claude FarréSection of Molecular Biology, Division of Biological Sciences, University of California, San Diego, La Jolla, CA.ORCID 0000-0001-8785-6474
Suresh SubramaniSection of Molecular Biology, Division of Biological Sciences, University of California, San Diego, La Jolla, CA ssubramani@ucsd.edu.ORCID 0000-0003-0180-1742
University of California San Diego · US

Funding

TARGETING OF PROTEINS INTO PEROXISOMESR01DK041737 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AITCHISON, JOHN D., SUBRAMANI, SURESH · 1990 to 2025
$8.4M
NIDDK NIH HHS R01 DK041737
6 · The paper itself

Abstract

Most proteins destined for the peroxisomal matrix depend on the peroxisomal targeting signals (PTSs), which require the PTS receptor PEX5, whose deficiency causes fatal human peroxisomal biogenesis disorders (PBDs).

Indexed as

AnimalsApoptosisGenetic Predisposition to DiseaseHEK293 CellsHep G2 CellsHumansMiceMulibrey NanismMutationNuclear ProteinsOrganelle BiogenesisOxidative StressPeroxisomesPeroxisome-Targeting Signal 1 ReceptorPhenotypeProteasome Endopeptidase ComplexNuclear ProteinsPeroxisome-Targeting Signal 1 ReceptorPEX5 protein, humanPex5 protein, mouseProteasome Endopeptidase ComplexReceptors, Cytoplasmic and NuclearTRIM37 protein, humanTripartite Motif ProteinsUbiquitin-Protein Ligases

Identifiers

PMID28724525
PMCPMC5584156
OpenAlexW2738059554

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.