ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2017
Population Genetic Structure of the Cayo Santiago Colony of Rhesus Macaques (
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Comparing the genomic inbreeding of an isolated rhesus macaque study population to wild populations.bioRxiv : the preprint server for biology · 2026Article
- Temporal Changes in Vertebral Morphology of the Free-Ranging Rhesus Macaques From Cayo Santiago, Puerto Rico.American journal of biological anthropology · 2026Article
- A Comparative Analysis of the Genetic Structures of Rhesus Macaques (Macaca mulatta) Kept in Enclosure-Based Systems and Semi-Natural Settings.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Next-Generation Short-Read Sequencing Reveals Impacts on Major Histocompatibility Complex Diversity Resulting From Differences in Captive Rhesus Macaque (Macaca Mulatta) Colony Expansion Strategies.American journal of primatology · 2026Article
- Pterion variation in the skulls of rhesus macaques from Cayo Santiago: Inheritance, development, and pathology.Anatomical record (Hoboken, N.J. : 2007) · 2024Article
- Pedigree Data from Six Rhesus Macaque (Journal of the American Association for Laboratory Animal Science : JAALAS · 2023Article
- Same-sex sociosexual behaviour is widespread and heritable in male rhesus macaques.Nature ecology & evolution · 2023Article
- Coming to the Caribbean-acclimation of Rhesus macaques (Macaca mulatta) at Cayo Santiago.American journal of biological anthropology · 2023Article
- Infection order outweighs the role of CD4iScience · 2022Article
- Article
- Variation in the Mu-Opioid Receptor (OPRM1) and Offspring Sex Are Associated With Maternal Behavior in Rhesus Macaques (Frontiers in behavioral neuroscience · 2022Article
- Determination of major histocompatibility class I and class II genetic composition of the Caribbean Primate Center specific pathogen-free rhesus macaque (Macaca mulatta) colony based on massively parallel sequencing.Journal of medical primatology · 2018Article
- Evaluating the genetic status of a closed colony of titi monkeys (Callicebus cupreus) using multigenerational pedigrees.Journal of medical primatology · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The rhesus macaque population at Cayo Santiago increases annually and is in urgent need of control. In-depth assessments of the colony's population genetic and pedigree structures provide a starting point for improving the colony's long-term management program. We evaluated the degree of genetic variation and coefficients of inbreeding and kinship of the Cayo Santiago colony by using pedigree and short tandem repeat (STR) data from 4738 rhesus macaques, which represent 7 extant social groups and a group of migrant males. Information on each animal's parentage, sex, birth date, and date of death or removal from the island were used to generate estimates of mean kinship, kinship value, gene value, genome uniqueness (GU), founder equivalents (fe), and founder genome equivalents (fg). Pedigree and STR analyses revealed that the social groups have not differentiated genetically from each other due to male-mediated gene flow (that is, FST estimates were in the negative range) and exhibit sufficient genetic variation, with mean estimates of allele numbers and observed and expected heterozygosity of 6.57, 0.72, and 0.70, respectively. Estimates of GU, fe, and fg show that a high effective number of founders has affected the colony's current genetic structure in a positive manner. As demographic changes occur, genetic and pedigree matrices need to be monitored consistently to ensure the health and wellbeing of the Cayo Santiago colony.
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28724489PMC5517329What OpenQuestion holds
Registered trials
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