ArticlePublic health nutrition2017
A combined high-sugar and high-saturated-fat dietary pattern is associated with more depressive symptoms in a multi-ethnic population: the HELIUS (Healthy Life in an Urban Setting) study.
Article in Public health nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Circadian Influences on the Habenula and Their Potential Contribution to Neuropsychiatric Disorders.Frontiers in behavioral neuroscience · 2021Pooled it
- Beyond Psychological Trauma: Associations of Nutritional Status with Depression in Child and Adolescent Victims of Crime.Healthcare (Basel, Switzerland) · 2026Article
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- Associations of nutritional habits, lifestyle, and demographic factors with mental health outcomes among university students in Lebanon: a cross-sectional study.BMC public health · 2025Article
- Understanding food addiction through the lens of psychological well-being, self-control, and eating behavior: a cross-sectional study.Journal of eating disorders · 2025Article
- Cohort Profile Update: The Healthy Life in an Urban Setting (HELIUS) Study.International journal of epidemiology · 2025Article
- Association between free sugars intake and early psychopathological problems.Journal of child health care : for professionals working with children in the hospital and community · 2024Article
- Testing the causal relationship of fat and sugar intake with depression and cortisol: a Mendelian Randomisation study.Translational psychiatry · 2024Article
- Association between dietary sugar intake and depression in US adults: a cross-sectional study using data from the National Health and Nutrition Examination Survey 2011-2018.BMC psychiatry · 2024Article
- Dietary Factors Associated with Depressive Symptoms in Midlife Women 40-50 Years of Age Living in the United States.Women's health reports (New Rochelle, N.Y.) · 2024Article
- Article
- Effects of Fructose and Palmitic Acid on Gene Expression inInternational journal of molecular sciences · 2023Article
- Interaction of fatty acid quality indices and genes related to lipid homeostasis on mental health among overweight and obese women.Scientific reports · 2023Article
- Appropriate Macronutrients or Mineral Elements Are Beneficial to Improve Depression and Reduce the Risk of Depression.International journal of molecular sciences · 2023Review
- Catering Work Profession and Medico-Oral Health: A Study on 603 Subjects.Healthcare (Basel, Switzerland) · 2021Article
- Association between dietary energy density with mental health and sleep quality in women with overweight/obesity.BMC research notes · 2020Article
- Association of food groups with depression and anxiety disorders.European journal of nutrition · 2020Article
- Prenatal Developmental Origins of Future Psychopathology: Mechanisms and Pathways.Annual review of clinical psychology · 2019Review
- Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify a high-sugar (HS) dietary pattern, a high-saturated-fat (HF) dietary pattern and a combined high-sugar and high-saturated-fat (HSHF) dietary pattern and to explore if these dietary patterns are associated with depressive symptoms.
designWe used data from the HELIUS (Healthy Life in an Urban Setting) study and included 4969 individuals aged 18-70 years. Diet was assessed using four ethnic-specific FFQ. Dietary patterns were derived using reduced rank regression with mono- and disaccharides, saturated fat and total fat as response variables. The nine-item Patient Health Questionnaire (PHQ-9) was used to assess depressive symptoms by using continuous scores and depressed mood (identified using the cut-off point: PHQ-9 sum score ≥10).
settingThe Netherlands.
resultsThree dietary patterns were identified; an HSHF dietary pattern (including chocolates, red meat, added sugars, high-fat dairy products, fried foods, creamy sauces), an HS dietary pattern (including sugar-sweetened beverages, added sugars, fruit (juices)) and an HF dietary pattern (including high-fat dairy products, butter). When comparing extreme quartiles, consumption of an HSHF dietary pattern was associated with more depressive symptoms (Q1 v. Q4: β=0·18, 95 % CI 0·07, 0·30, P=0·001) and with higher odds of depressed mood (Q1 v. Q4: OR=2·36, 95 % CI 1·19, 4·66, P=0·014). No associations were found between consumption of the remaining dietary patterns and depressive symptoms.
conclusionsHigher consumption of an HSHF dietary pattern is associated with more depressive symptoms and with depressed mood. Our findings reinforce the idea that the focus should be on dietary patterns that are high in both sugar and saturated fat.
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