Evidence map›Paper›PMID 28724288›Full record

ArticleJournal of the American Chemical Society2017

Proton-Based Structural Analysis of a Heptahelical Transmembrane Protein in Lipid Bilayers.

Daniela Lalli, Matthew N Idso, Loren B Andreas, Sunyia Hussain, Naomi Baxter, Songi Han, Bradley F Chmelka, Guido Pintacuda

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 57 citations in OpenAlex.

  1. Plant structural biology: Emerging technologies and future biological insights.The Plant journal : for cell and molecular biology · 2026
    Review
  2. bioRxiv : the preprint server for biology · 2025
    Article
  3. Cross polarization stability in multidimensional NMR spectroscopy of biological solids.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Chemical reviews · 2022
    Review
  10. MgeLife · 2022
    Article
  11. Solid-State NMR Spectroscopy on Microbial Rhodopsins.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  12. Article
  13. Review
  14. Article
  15. Solid-state NMR spectroscopy.Nature reviews. Methods primers · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. High-sensitivity protein solid-state NMR spectroscopy.Current opinion in structural biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Daniela LalliCentre de RMN à Très Hauts Champs, Institut des Sciences Analytiques (UMR 5280 - CNRS, ENS Lyon, UCB Lyon 1), Université de Lyon , 69100 Villeurbanne, France.
Matthew N IdsoDepartment of Chemical Engineering, University of California , Santa Barbara, California 93106, United States.
Loren B AndreasCentre de RMN à Très Hauts Champs, Institut des Sciences Analytiques (UMR 5280 - CNRS, ENS Lyon, UCB Lyon 1), Université de Lyon , 69100 Villeurbanne, France.
Sunyia HussainDepartment of Chemical Engineering, University of California , Santa Barbara, California 93106, United States.
Naomi BaxterDepartment of Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Songi HanDepartment of Chemical Engineering, University of California , Santa Barbara, California 93106, United States.
Bradley F ChmelkaDepartment of Chemical Engineering, University of California , Santa Barbara, California 93106, United States.ORCID 0000-0002-4450-6949
Guido PintacudaCentre de RMN à Très Hauts Champs, Institut des Sciences Analytiques (UMR 5280 - CNRS, ENS Lyon, UCB Lyon 1), Université de Lyon , 69100 Villeurbanne, France.ORCID 0000-0001-7757-2144
University of California, Santa Barbara · USUniversité Claude Bernard Lyon 1 · FR

Funding

The Role of Lipid Membrane and Hydration on the Oligomerization and Function of PR and A2AR01GM116128 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI HAN, SONGI · 2015 to 2018
$1.5M
European Research Council 648974NIGMS NIH HHS R01 GM116128
6 · The paper itself

Abstract

The structures and properties of membrane proteins in lipid bilayers are expected to closely resemble those in native cell-membrane environments, although they have been difficult to elucidate. By performing solid-state NMR measurements at very fast (100 kHz) magic-angle spinning rates and at high (23.5 T) magnetic field, severe sensitivity and resolution challenges are overcome, enabling the atomic-level characterization of membrane proteins in lipid environments. This is demonstrated by extensive

Indexed as

ProtonsLipid BilayersMembrane ProteinsNuclear Magnetic Resonance, BiomolecularProtein ConformationLipid BilayersMembrane ProteinsProtons

Identifiers

PMID28724288
PMCPMC5741281
OpenAlexW2738002072

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.